Protein-tyrosine phosphatase 1B
Checkout as a new customer
Creating an account has many benefits:
- See order and shipping status
- Track order history
- Check out faster
Checkout using your account
ID: ALA2371
Type: SINGLE PROTEIN
Synonyms: 3.1.3.48 | Protein-tyrosine phosphatase 1B | PTP-1B | Ptpn1 | Tyrosine-protein phosphatase non-receptor type 1
Organism: Rattus norvegicus
Species Group: Rattus norvegicus
Protein Target Classification: Enzyme / Phosphatase / Protein Phosphatase / Tyrosine protein phosphatase
Description | Relationship | Accession |
---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 | PROTEIN | P20417 |
Name:
2-(3-{4-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-but-2-enyl)-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C24H20F3N3O5
M.W.:
487.43
Type:
Small molecule
AlogP:
4.79
Polar Surface Area:
103.26
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.40
Name:
2-(3-{3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-but-2-enyl)-[1,2,4]thiadiazolidine-3,5-dione
Mol. Formula:
C24H20F3N3O4S
M.W.:
503.50
Type:
Small molecule
AlogP:
5.26
Polar Surface Area:
90.12
HBA:
7
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.37
Name:
2-(3-{3-[2-(4-Chloro-phenyl)-5-methyl-oxazol-4-ylmethoxy]-phenyl}-1-methyl-allyl)-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C23H20ClN3O5
M.W.:
453.88
Type:
Small molecule
AlogP:
4.60
Polar Surface Area:
103.26
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.44
Name:
2-(3-{3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-but-2-enyl)-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C24H20F3N3O5
M.W.:
487.43
Type:
Small molecule
AlogP:
4.79
Polar Surface Area:
103.26
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.40
Name:
2-[3-(4-{2-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-ethoxy}-phenyl)-but-2-enyl]-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C25H22F3N3O5
M.W.:
501.46
Type:
Small molecule
AlogP:
4.84
Polar Surface Area:
103.26
HBA:
7
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.37
Name:
2-(3-{3-[5-Methyl-2-(4-trifluoromethoxy-phenyl)-oxazol-4-ylmethoxy]-phenyl}-butyl)-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C24H22F3N3O6
M.W.:
505.45
Type:
Small molecule
AlogP:
4.76
Polar Surface Area:
112.49
HBA:
8
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.35
Name:
2-(3-(4-Fluoro-phenyl)-3-{3-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-allyl)-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C29H21F4N3O5
M.W.:
567.50
Type:
Small molecule
AlogP:
5.96
Polar Surface Area:
103.26
HBA:
7
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.23
Name:
2-(3-{3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-4-phenyl-but-2-enyl)-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C30H24F3N3O5
M.W.:
563.53
Type:
Small molecule
AlogP:
6.02
Polar Surface Area:
103.26
HBA:
7
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.24
Name:
2-(3-{3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-hex-2-enyl)-[1,2,4]oxadiazolidine-3,5-dione
Mol. Formula:
C26H24F3N3O5
M.W.:
515.49
Type:
Small molecule
AlogP:
5.57
Polar Surface Area:
103.26
HBA:
7
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.31
Name:
[2-(3-{3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-phenyl}-undec-2-enyl)-3,5-dioxo-[1,2,4]oxadiazolidin-4-yl]-acetic acid
Mol. Formula:
C33H36F3N3O7
M.W.:
643.66
Type:
Small molecule
AlogP:
7.08
Polar Surface Area:
129.70
HBA:
9
HBD:
1
#RO5 Violations:
2
#Rotatable Bonds:
16
Passes Ro3:
N
QED Weighted:
0.13