ID: ALA2553
Type: SINGLE PROTEIN
Synonyms: 2.7.11.1 | 90 kDa ribosomal protein S6 kinase 1 | MAP kinase-activated protein kinase 1a | MAPK-activated protein kinase 1a | MAPKAP kinase 1a | MAPKAPK-1a | MAPKAPK1A | p90-RSK 1 | p90RSK1 | p90S6K | Ribosomal protein S6 kinase alpha-1 | Ribosomal S6 kinase 1 | RPS6KA1 | RSK-1 | RSK1 | S6K-alpha-1
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Enzyme / Kinase / Protein Kinase / AGC protein kinase group / AGC protein kinase RSK family / AGC protein kinase RSK subfamily
Description | Relationship | Accession |
---|---|---|
Ribosomal protein S6 kinase alpha-1 | PROTEIN | Q15418 |
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
---|
Name | Specifications | Species reactivity | species | Application | View Details |
---|
Name:
2-((3,5-difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one
Mol. Formula:
C19H23F2N5O2
M.W.:
391.42
Type:
Small molecule
AlogP:
3.42
Polar Surface Area:
81.59
HBA:
6
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.76
Name:
N-(3-((5-iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide
Mol. Formula:
C23H26IN7O2S
M.W.:
591.48
Type:
Small molecule
AlogP:
4.75
Polar Surface Area:
111.28
HBA:
7
HBD:
4
#RO5 Violations:
1
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.21
Name:
3-(2-aminoethyl)-5-(2-ethoxybenzylidene)thiazolidine-2,4-dione
Mol. Formula:
C14H16N2O3S
M.W.:
292.36
Type:
Small molecule
AlogP:
2.08
Polar Surface Area:
72.63
HBA:
5
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.84
Name:
3-(2-aminoethyl)-5-(4-fluorobenzylidene)thiazolidine-2,4-dione
Mol. Formula:
C12H11FN2O2S
M.W.:
266.30
Type:
Small molecule
AlogP:
1.82
Polar Surface Area:
63.40
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.85
Name:
3-(2-aminoethyl)-5-(3-fluorobenzylidene)thiazolidine-2,4-dione
Mol. Formula:
C12H11FN2O2S
M.W.:
266.30
Type:
Small molecule
AlogP:
1.82
Polar Surface Area:
63.40
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.85
Name:
3-(2-aminoethyl)-5-(4-nitrobenzylidene)thiazolidine-2,4-dione
Mol. Formula:
C12H11N3O4S
M.W.:
293.30
Type:
Small molecule
AlogP:
1.59
Polar Surface Area:
106.54
HBA:
6
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.51
Name:
3-(2-aminoethyl)-5-(3-nitrobenzylidene)thiazolidine-2,4-dione
Mol. Formula:
C12H11N3O4S
M.W.:
293.30
Type:
Small molecule
AlogP:
1.59
Polar Surface Area:
106.54
HBA:
6
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.51
Name:
3-(2-(dimethylamino)ethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione
Mol. Formula:
C16H20N2O3S
M.W.:
320.41
Type:
Small molecule
AlogP:
2.68
Polar Surface Area:
49.85
HBA:
5
HBD:
0
#RO5 Violations:
0
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.75
Name:
N-(2-(5-(4-ethoxybenzylidene)-2,4-dioxothiazolidin-3-yl)ethyl)acetamide
Mol. Formula:
C16H18N2O4S
M.W.:
334.40
Type:
Small molecule
AlogP:
2.26
Polar Surface Area:
75.71
HBA:
5
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.81
Name:
US8889696, Staurosporine::US9051313, Staurosporine
Mol. Formula:
C27H24N4O3
M.W.:
452.51
Type:
Small molecule
AlogP:
4.75
Polar Surface Area:
72.94
HBA:
6
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.41