ID: ALA257
Type: SINGLE PROTEIN
Synonyms: Agtr2 | Angiotensin II type-2 receptor | AT2 receptor | Type-2 angiotensin II receptor
Organism: Rattus norvegicus
Species Group: Rattus norvegicus
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Peptide receptor (family A GPCR) / Short peptide receptor (family A GPCR) / Angiotensin receptor
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA2094112 | SUBSET OF | Angiotensin II receptor | PROTEIN FAMILY |
Description | Relationship | Accession |
---|---|---|
Type-2 angiotensin II receptor | PROTEIN | P35351 |
Name | Specifications | Species reactivity | species | Application | View Details |
---|---|---|---|---|---|
RBP1 Mouse mAb | Human,Mouse,Rat | Mouse | Expand⌵ |
Name:
[2-Butyl-5-chloro-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-acetic acid
Mol. Formula:
C16H18Cl2N2O2
M.W.:
341.24
Type:
Small molecule
AlogP:
4.21
Polar Surface Area:
55.12
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.82
Name:
3-[2-Butyl-3-(2-hydroxy-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid
Mol. Formula:
C22H24N2O3S
M.W.:
396.51
Type:
Small molecule
AlogP:
4.75
Polar Surface Area:
75.35
HBA:
5
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.51
Name:
3-[2-Butyl-3-(4-hydroxy-3-methyl-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid
Mol. Formula:
C23H26N2O3S
M.W.:
410.54
Type:
Small molecule
AlogP:
5.06
Polar Surface Area:
75.35
HBA:
5
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.48
Name:
2-Benzyl-3-[2-butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-acrylic acid
Mol. Formula:
C24H25ClN2O2
M.W.:
408.93
Type:
Small molecule
AlogP:
5.64
Polar Surface Area:
55.12
HBA:
3
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.47
Name:
3-[2-Butyl-3-(4-nitro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid
Mol. Formula:
C22H23N3O4S
M.W.:
425.51
Type:
Small molecule
AlogP:
4.95
Polar Surface Area:
98.26
HBA:
6
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.28
Name:
[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-acetic acid
Mol. Formula:
C16H19ClN2O2
M.W.:
306.79
Type:
Small molecule
AlogP:
3.55
Polar Surface Area:
55.12
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.85
Name:
3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-acrylic acid
Mol. Formula:
C17H19ClN2O2
M.W.:
318.80
Type:
Small molecule
AlogP:
4.03
Polar Surface Area:
55.12
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.78
Name:
2-({1-[2-{2-[2-{2-[5-Guanidino-2-(2-methylamino-acetylamino)-pentanoylamino]-3-methyl-butyrylamino}-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-3-(3H-imidazol-4-yl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-phenyl-propionic acid
Mol. Formula:
C49H71N13O10
M.W.:
1002.19
Type:
Protein
Name:
2-[2-Butyl-5-(2-carboxy-3-thiophen-2-yl-propenyl)-imidazol-1-ylmethyl]-benzoic acid
Mol. Formula:
C23H24N2O4S
M.W.:
424.52
Type:
Small molecule
AlogP:
4.74
Polar Surface Area:
92.42
HBA:
5
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.46