ID: ALA2760
Type: SINGLE PROTEIN
Synonyms: 3.1.4.12 | 3.1.4.3 | Acid sphingomyelinase | ASM | aSMase | SMPD1 | Sphingomyelin phosphodiesterase | Sphingomyelin phosphodiesterase, processed form | Synonyms=ASM
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Enzyme / Phosphodiesterase
Description | Relationship | Accession |
---|---|---|
Sphingomyelin phosphodiesterase | PROTEIN | P17405 |
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
---|
Name:
{2-[Hydroxy-((E)-(2S,3R)-3-hydroxy-2-icosanoylamino-octadec-4-enyloxy)-phosphoryloxy]-ethyl}-trimethyl-ammonium
Mol. Formula:
C43H87N2O6P
M.W.:
759.15
Type:
Small molecule
AlogP:
11.34
Polar Surface Area:
107.92
HBA:
6
HBD:
2
#RO5 Violations:
2
#Rotatable Bonds:
40
Passes Ro3:
N
QED Weighted:
0.03
Name:
[2-(5-Dimethylamino-naphthalene-1-sulfonylamino)-ethyl]-{2-[hydroxy-(3-hydroxy-2-icosanoylamino-octadec-4-enyloxy)-phosphoryloxy]-ethyl}-dimethyl-ammonium
Mol. Formula:
C56H102N4O8PS+
M.W.:
1022.49
Type:
Small molecule
Name:
Phosphoric acid 3-hydroxy-2-{6-[5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-hexanoylamino}-octadec-4-enyl ester 6-(7-nitro-benzo[1,2,5]oxadiazol-4-ylamino)-hexyl ester
Mol. Formula:
C46H77N8O11PS
M.W.:
981.21
Type:
Small molecule
AlogP:
8.74
Polar Surface Area:
269.41
HBA:
14
HBD:
7
#RO5 Violations:
4
#Rotatable Bonds:
39
Passes Ro3:
N
QED Weighted:
0.01
Name:
Phosphoric acid 4-(5-dimethylamino-naphthalene-1-sulfonylamino)-butyl ester 3-hydroxy-2-{6-[5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-hexanoylamino}-octadec-4-enyl ester
Mol. Formula:
C50H83N6O10PS2
M.W.:
1023.35
Type:
Small molecule
Name:
(2,4-Dihydroxy-5-methoxy-phenyl)-[2,4,6-trihydroxy-3-(3-methyl-but-2-enyl)-phenyl]-methanone
Mol. Formula:
C19H20O7
M.W.:
360.36
Type:
Small molecule
AlogP:
2.96
Polar Surface Area:
127.45
HBA:
7
HBD:
5
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.41
Name:
[4,6-Dihydroxy-3-methoxy-2-(3-methyl-but-2-enyl)-phenyl]-(2,4,6-trihydroxy-phenyl)-methanone
Mol. Formula:
C19H20O7
M.W.:
360.36
Type:
Small molecule
AlogP:
2.96
Polar Surface Area:
127.45
HBA:
7
HBD:
5
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.41
Name:
1,3,6-Trihydroxy-7-methoxy-2-(3-methyl-but-2-enyl)-xanthen-9-one
Mol. Formula:
C19H18O6
M.W.:
342.35
Type:
Small molecule
AlogP:
3.58
Polar Surface Area:
100.13
HBA:
6
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.50
Name:
[4,6-Dihydroxy-3-methoxy-2-(3-methyl-but-2-enyl)-phenyl]-[2,4,6-trihydroxy-3-(3-methyl-but-2-enyl)-phenyl]-methanone
Mol. Formula:
C24H28O7
M.W.:
428.48
Type:
Small molecule
AlogP:
4.47
Polar Surface Area:
127.45
HBA:
7
HBD:
5
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.33
Name:
1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2-enyl)-xanthen-9-one
Mol. Formula:
C24H26O6
M.W.:
410.47
Type:
Small molecule
AlogP:
5.09
Polar Surface Area:
100.13
HBA:
6
HBD:
3
#RO5 Violations:
1
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.40
Name:
3,6,8-Trihydroxy-2-methoxy-1-(3-methyl-but-2-enyl)-xanthen-9-one
Mol. Formula:
C19H18O6
M.W.:
342.35
Type:
Small molecule
AlogP:
3.58
Polar Surface Area:
100.13
HBA:
6
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.50