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Choline transporter

Name And Classification

ID:  ALA3013

Type:  SINGLE PROTEIN

Synonyms:   CHT | Cht1 | Hemicholinium-3-sensitive choline transporter | High affinity choline transporter 1 | Slc5a7 | Solute carrier family 5 member 7

Organism:  Mus musculus

Species Group:  Mus musculus

Protein Target Classification:   Transporter / Electrochemical transporter / SLC superfamily of solute carriers / SLC05 family of sodium-dependent glucose transporters

Target Components

DescriptionRelationshipAccession
High affinity choline transporter 1PROTEINQ8BGY9

Associated Active Ligands

  1. Tetrahydrouridine
    ALA125756

    Name:
    1-Ethyl-1-(2-hydroxy-ethyl)-aziridinium chloride

    Mol. Formula:
    C6H14ClNO

    M.W.:
    151.64

    Type:
    Small molecule

    AlogP:
    -0.17

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.40

    DETAILS
  2. Tetrahydrouridine
    ALA123573

    Name:
    1-Cyclopropyl-1-(2-hydroxy-ethyl)-aziridinium chloride

    Mol. Formula:
    C7H14ClNO

    M.W.:
    163.65

    Type:
    Small molecule

    AlogP:
    -0.03

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.42

    DETAILS
  3. Tetrahydrouridine
    ALA126202

    Name:
    1-(2-Hydroxy-ethyl)-1-isobutyl-aziridinium chloride

    Mol. Formula:
    C8H18ClNO

    M.W.:
    179.69

    Type:
    Small molecule

    AlogP:
    0.47

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.45

    DETAILS
  4. Tetrahydrouridine
    ALA340441

    Name:
    1-(2-Hydroxy-ethyl)-1-isopropyl-aziridinium chloride

    Mol. Formula:
    C7H16ClNO

    M.W.:
    165.66

    Type:
    Small molecule

    AlogP:
    0.22

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.43

    DETAILS
  5. Tetrahydrouridine
    ALA125710

    Name:
    1-(2-Hydroxy-ethyl)-1-propyl-aziridinium chloride

    Mol. Formula:
    C7H16ClNO

    M.W.:
    165.66

    Type:
    Small molecule

    AlogP:
    0.22

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.43

    DETAILS
  6. Tetrahydrouridine
    ALA125711

    Name:
    1-Butyl-1-(2-hydroxy-ethyl)-aziridinium chloride

    Mol. Formula:
    C8H18ClNO

    M.W.:
    179.69

    Type:
    Small molecule

    AlogP:
    0.61

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  7. Tetrahydrouridine
    ALA1209421

    Name:
    N,N,N-trimethylbenzenaminium

    Mol. Formula:
    C9H14ClN

    M.W.:
    171.67

    Type:
    Small molecule

    AlogP:
    1.88

    Polar Surface Area:
    0.00

    HBA:
    0

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    Y

    QED Weighted:
    0.52

    DETAILS
  8. Tetrahydrouridine
    ALA1209422

    Name:
    3-hydroxy-N,N,N-trimethylpropan-1-aminium

    Mol. Formula:
    C6H16ClNO

    M.W.:
    153.65

    Type:
    Small molecule

    AlogP:
    0.07

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.52

    DETAILS
  9. Tetrahydrouridine
    ALA1209423

    Name:
    4-hydroxy-N,N,N-trimethylbutan-1-aminium

    Mol. Formula:
    C7H18ClNO

    M.W.:
    167.68

    Type:
    Small molecule

    AlogP:
    0.47

    Polar Surface Area:
    20.23

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.44

    DETAILS
  10. Tetrahydrouridine
    ALA1209424

    Name:
    3-hydroxy-N,N-dimethylpropan-1-aminium

    Mol. Formula:
    C5H13NO

    M.W.:
    103.17

    Type:
    Small molecule

    AlogP:
    -0.07

    Polar Surface Area:
    23.47

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.54

    DETAILS