Your company account is blocked and you cannot place orders. If you have questions, please contact your company administrator.

Protein kinase N2

Name And Classification

ID:  ALA3032

Type:  SINGLE PROTEIN

Synonyms:   2.7.11.13 | PKN gamma | PKN2 | PRK2 | PRKCL2 | Protein kinase C-like 2 | Protein-kinase C-related kinase 2 | Serine/threonine-protein kinase N2

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Enzyme / Kinase / Protein Kinase / AGC protein kinase group / AGC protein kinase PKN family

Target Components

DescriptionRelationshipAccession
Serine/threonine-protein kinase N2PROTEINQ16513

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Active Ligands

  1. Tetrahydrouridine
    ALA590322

    Name:
    3,4-Dimethoxy-N-[3-(3-piperidin-3-yl-propionylamino)-benzyl]-benzamide

    Mol. Formula:
    C24H31N3O4

    M.W.:
    425.53

    Type:
    Small molecule

    AlogP:
    3.35

    Polar Surface Area:
    88.69

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  2. Tetrahydrouridine
    ALA589118

    Name:
    3-[3-(3-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin-3-yl-ethyl)-benzamide

    Mol. Formula:
    C23H27N5O2

    M.W.:
    405.50

    Type:
    Small molecule

    AlogP:
    3.00

    Polar Surface Area:
    106.05

    HBA:
    4

    HBD:
    4

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  3. Tetrahydrouridine
    ALA589359

    Name:
    3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin-3-yl-ethyl)-benzamide

    Mol. Formula:
    C23H27N5O2

    M.W.:
    405.50

    Type:
    Small molecule

    AlogP:
    3.00

    Polar Surface Area:
    106.05

    HBA:
    4

    HBD:
    4

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS
  4. Tetrahydrouridine
    ALA600852

    Name:
    3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)-benzamide

    Mol. Formula:
    C25H25N5O3

    M.W.:
    443.51

    Type:
    Small molecule

    AlogP:
    3.01

    Polar Surface Area:
    125.35

    HBA:
    4

    HBD:
    5

    #RO5 Violations:
    0

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.40

    DETAILS
  5. Tetrahydrouridine
    ALA2425144

    Name:
    1-(4-(6-amino-9H-purin-9-yl)phenyl)-3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)urea

    Mol. Formula:
    C26H27N9O

    M.W.:
    481.56

    Type:
    Small molecule

    AlogP:
    4.83

    Polar Surface Area:
    128.57

    HBA:
    8

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.34

    DETAILS
  6. Tetrahydrouridine
    ALA3785500

    Name:
    5-(3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl)-7-((cis)-3-(azetidin-1-ylmethyl)cyclobutyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

    Mol. Formula:
    C27H33N5O2

    M.W.:
    459.59

    Type:
    Small molecule

    AlogP:
    4.43

    Polar Surface Area:
    78.43

    HBA:
    7

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.56

    DETAILS
  7. Tetrahydrouridine
    ALA3786167

    Name:
    1-(4-((cis)-3-(4-amino-5-(2-fluoro-3-(((S)-tetrahydrofuran-2-yl)methoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclobutyl)piperazin-1-yl)ethanone

    Mol. Formula:
    C27H33FN6O3

    M.W.:
    508.60

    Type:
    Small molecule

    AlogP:
    3.25

    Polar Surface Area:
    98.74

    HBA:
    8

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    6

    Passes Ro3:
    N

    QED Weighted:
    0.55

    DETAILS
  8. Tetrahydrouridine
    ALA4632420

    Name:
    Methyl 2-(4-pyridyl)-1H-benzimidazole-4-carboxylate

    Mol. Formula:
    C14H11N3O2

    M.W.:
    253.26

    Type:
    Unknown

    AlogP:
    2.41

    Polar Surface Area:
    67.87

    HBA:
    4

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.71

    DETAILS
  9. Tetrahydrouridine
    ALA4634210

    Name:
    2-(4-Pyridyl)-1H-benzimidazole-5-carbonitrile

    Mol. Formula:
    C13H8N4

    M.W.:
    220.24

    Type:
    Unknown

    AlogP:
    2.50

    Polar Surface Area:
    65.36

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.68

    DETAILS
  10. Tetrahydrouridine
    ALA4635777

    Name:
    N-Methyl-2-(4-pyridyl)-1H-benzimidazole-4-carboxamide

    Mol. Formula:
    C14H12N4O

    M.W.:
    252.28

    Type:
    Unknown

    AlogP:
    1.98

    Polar Surface Area:
    70.67

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.73

    DETAILS