ID: ALA3032
Type: SINGLE PROTEIN
Synonyms: 2.7.11.13 | PKN gamma | PKN2 | PRK2 | PRKCL2 | Protein kinase C-like 2 | Protein-kinase C-related kinase 2 | Serine/threonine-protein kinase N2
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Enzyme / Kinase / Protein Kinase / AGC protein kinase group / AGC protein kinase PKN family
Description | Relationship | Accession |
---|---|---|
Serine/threonine-protein kinase N2 | PROTEIN | Q16513 |
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
---|
Name:
3,4-Dimethoxy-N-[3-(3-piperidin-3-yl-propionylamino)-benzyl]-benzamide
Mol. Formula:
C24H31N3O4
M.W.:
425.53
Type:
Small molecule
AlogP:
3.35
Polar Surface Area:
88.69
HBA:
5
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.57
Name:
3-[3-(3-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin-3-yl-ethyl)-benzamide
Mol. Formula:
C23H27N5O2
M.W.:
405.50
Type:
Small molecule
AlogP:
3.00
Polar Surface Area:
106.05
HBA:
4
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.57
Name:
3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin-3-yl-ethyl)-benzamide
Mol. Formula:
C23H27N5O2
M.W.:
405.50
Type:
Small molecule
AlogP:
3.00
Polar Surface Area:
106.05
HBA:
4
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.57
Name:
3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(1,2,3,4-tetrahydroisoquinolin-7-yl)-benzamide
Mol. Formula:
C25H25N5O3
M.W.:
443.51
Type:
Small molecule
AlogP:
3.01
Polar Surface Area:
125.35
HBA:
4
HBD:
5
#RO5 Violations:
0
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.40
Name:
1-(4-(6-amino-9H-purin-9-yl)phenyl)-3-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)urea
Mol. Formula:
C26H27N9O
M.W.:
481.56
Type:
Small molecule
AlogP:
4.83
Polar Surface Area:
128.57
HBA:
8
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.34
Name:
5-(3-(7-oxabicyclo[2.2.1]heptan-1-ylmethoxy)phenyl)-7-((cis)-3-(azetidin-1-ylmethyl)cyclobutyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Mol. Formula:
C27H33N5O2
M.W.:
459.59
Type:
Small molecule
AlogP:
4.43
Polar Surface Area:
78.43
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.56
Name:
1-(4-((cis)-3-(4-amino-5-(2-fluoro-3-(((S)-tetrahydrofuran-2-yl)methoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclobutyl)piperazin-1-yl)ethanone
Mol. Formula:
C27H33FN6O3
M.W.:
508.60
Type:
Small molecule
AlogP:
3.25
Polar Surface Area:
98.74
HBA:
8
HBD:
1
#RO5 Violations:
1
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.55
Name:
Methyl 2-(4-pyridyl)-1H-benzimidazole-4-carboxylate
Mol. Formula:
C14H11N3O2
M.W.:
253.26
Type:
Unknown
AlogP:
2.41
Polar Surface Area:
67.87
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.71
Name:
N-Methyl-2-(4-pyridyl)-1H-benzimidazole-4-carboxamide
Mol. Formula:
C14H12N4O
M.W.:
252.28
Type:
Unknown
AlogP:
1.98
Polar Surface Area:
70.67
HBA:
3
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.73