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Anandamide amidohydrolase

Name And Classification

ID:  ALA3229

Type:  SINGLE PROTEIN

Synonyms:   3.1.1.- | 3.5.1.99 | Anandamide amidase | Anandamide amidohydrolase 1 | Faah | Faah1 | Fatty acid ester hydrolase | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1

Organism:  Rattus norvegicus

Species Group:  Rattus norvegicus

Protein Target Classification:   Enzyme / Hydrolase

Target Components

DescriptionRelationshipAccession
Fatty-acid amide hydrolase 1PROTEINP97612

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Active Ligands

  1. Tetrahydrouridine
    ALA15948

    Name:
    (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid bis-(2-hydroxy-ethyl)-amide

    Mol. Formula:
    C24H41NO3

    M.W.:
    391.60

    Type:
    Small molecule

    AlogP:
    4.95

    Polar Surface Area:
    60.77

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    18

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  2. Tetrahydrouridine
    ALA15150

    Name:
    (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid amide

    Mol. Formula:
    C20H33NO

    M.W.:
    303.49

    Type:
    Small molecule

    AlogP:
    5.62

    Polar Surface Area:
    43.09

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    14

    Passes Ro3:
    N

    QED Weighted:
    0.33

    DETAILS
  3. Tetrahydrouridine
    ALA35925

    Name:
    (Z)-1-Oxazolo[4,5-b]pyridin-2-yl-octadec-9-en-1-one

    Mol. Formula:
    C24H36N2O2

    M.W.:
    384.56

    Type:
    Small molecule

    AlogP:
    7.44

    Polar Surface Area:
    55.99

    HBA:
    4

    HBD:
    0

    #RO5 Violations:
    1

    #Rotatable Bonds:
    16

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  4. Tetrahydrouridine
    ALA290997

    Name:
    (Z)-1-Oxazolo[4,5-b]pyridin-2-yl-octadec-9-en-1-one O-methyl-oxime

    Mol. Formula:
    C25H39N3O2

    M.W.:
    413.61

    Type:
    Small molecule

    AlogP:
    7.61

    Polar Surface Area:
    60.51

    HBA:
    5

    HBD:
    0

    #RO5 Violations:
    1

    #Rotatable Bonds:
    17

    Passes Ro3:
    N

    QED Weighted:
    0.12

    DETAILS
  5. Tetrahydrouridine
    ALA36655

    Name:
    (Z)-2,2-Dimethyl-1-oxazol-2-yl-octadec-9-en-1-one

    Mol. Formula:
    C23H39NO2

    M.W.:
    361.57

    Type:
    Small molecule

    AlogP:
    7.53

    Polar Surface Area:
    43.10

    HBA:
    3

    HBD:
    0

    #RO5 Violations:
    1

    #Rotatable Bonds:
    16

    Passes Ro3:
    N

    QED Weighted:
    0.17

    DETAILS
  6. Tetrahydrouridine
    ALA37585

    Name:
    (Z)-1-Oxazolo[4,5-b]pyridin-2-yl-octadec-9-en-1-one oxime

    Mol. Formula:
    C24H37N3O2

    M.W.:
    399.58

    Type:
    Small molecule

    AlogP:
    7.44

    Polar Surface Area:
    71.51

    HBA:
    5

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    16

    Passes Ro3:
    N

    QED Weighted:
    0.10

    DETAILS
  7. Tetrahydrouridine
    ALA39306

    Name:
    N,N-Dimethyl-N'-[(Z)-1-oxazolo[4,5-b]pyridin-2-yl-octadec-9-en-(Z)-ylidene]-hydrazine

    Mol. Formula:
    C26H42N4O

    M.W.:
    426.65

    Type:
    Small molecule

    AlogP:
    7.53

    Polar Surface Area:
    54.52

    HBA:
    5

    HBD:
    0

    #RO5 Violations:
    1

    #Rotatable Bonds:
    17

    Passes Ro3:
    N

    QED Weighted:
    0.11

    DETAILS
  8. Tetrahydrouridine
    ALA37044

    Name:
    (Z)-2-Methyl-1-oxazol-2-yl-octadec-9-en-1-one

    Mol. Formula:
    C22H37NO2

    M.W.:
    347.54

    Type:
    Small molecule

    AlogP:
    7.14

    Polar Surface Area:
    43.10

    HBA:
    3

    HBD:
    0

    #RO5 Violations:
    1

    #Rotatable Bonds:
    16

    Passes Ro3:
    N

    QED Weighted:
    0.18

    DETAILS
  9. Tetrahydrouridine
    ALA39412

    Name:
    (Z)-1-Oxazol-2-yl-octadec-9-en-1-one

    Mol. Formula:
    C21H35NO2

    M.W.:
    333.52

    Type:
    Small molecule

    AlogP:
    6.89

    Polar Surface Area:
    43.10

    HBA:
    3

    HBD:
    0

    #RO5 Violations:
    1

    #Rotatable Bonds:
    16

    Passes Ro3:
    N

    QED Weighted:
    0.19

    DETAILS
  10. Tetrahydrouridine
    ALA39796

    Name:
    ((Z)-2-Octadec-9-enyl)-oxazolo[4,5-b]pyridine

    Mol. Formula:
    C24H38N2O

    M.W.:
    370.58

    Type:
    Small molecule

    AlogP:
    7.80

    Polar Surface Area:
    38.92

    HBA:
    3

    HBD:
    0

    #RO5 Violations:
    1

    #Rotatable Bonds:
    16

    Passes Ro3:
    N

    QED Weighted:
    0.22

    DETAILS