ID: ALA4227
Type: SINGLE PROTEIN
Synonyms: FMLP-R-I | FMLP-related receptor I | Formyl peptide receptor-like 1 | FPR2 | FPRH1 | FPRL1 | HM63 | Lipoxin A4 receptor | LXA4 receptor | LXA4R | N-formyl peptide receptor 2 | RFP
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Peptide receptor (family A GPCR) / N-formyl methionyl peptide receptor
ALA ID | Relationship | Pref Name | Target Type |
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Description | Relationship | Accession |
---|---|---|
N-formyl peptide receptor 2 | PROTEIN | P25090 |
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Name | Specifications | Species reactivity | species | Application | View Details |
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Name:
1-(4-bromophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Mol. Formula:
C18H17BrN4O2
M.W.:
401.26
Type:
Small molecule
AlogP:
3.89
Polar Surface Area:
68.06
HBA:
4
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.70
Name:
1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2,5-dihydro-1H-pyrazol-4-yl)urea
Mol. Formula:
C18H19ClN6O2
M.W.:
386.84
Type:
Small molecule
AlogP:
3.39
Polar Surface Area:
93.84
HBA:
6
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.72
Name:
1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)urea
Mol. Formula:
C23H22ClN5O2
M.W.:
435.92
Type:
Small molecule
AlogP:
5.15
Polar Surface Area:
80.95
HBA:
5
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.47
Name:
1-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(trifluoromethyl)phenyl)urea
Mol. Formula:
C24H22F3N5O2
M.W.:
469.47
Type:
Small molecule
AlogP:
5.51
Polar Surface Area:
80.95
HBA:
5
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.41
Name:
1-(1-(4,5-dihydrothiazol-2-yl)-3-isopropyl-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(trifluoromethyl)phenyl)urea
Mol. Formula:
C18H20F3N5O2S
M.W.:
427.45
Type:
Small molecule
AlogP:
3.92
Polar Surface Area:
80.42
HBA:
6
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.78
Name:
1-(4-chlorophenyl)-3-(1-(4,5-dihydrothiazol-2-yl)-3-isopropyl-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-4-yl)urea
Mol. Formula:
C17H20ClN5O2S
M.W.:
393.90
Type:
Small molecule
AlogP:
3.56
Polar Surface Area:
80.42
HBA:
6
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.84
Name:
1-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea
Mol. Formula:
C19H22N6O2S
M.W.:
398.49
Type:
Small molecule
AlogP:
3.46
Polar Surface Area:
93.84
HBA:
7
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.64
Name:
1-(4-chlorophenyl)-3-(3-ethyl-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea
Mol. Formula:
C19H19ClN4O2
M.W.:
370.84
Type:
Small molecule
AlogP:
4.04
Polar Surface Area:
68.06
HBA:
4
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.73
Name:
1-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea
Mol. Formula:
C24H25N5O2S
M.W.:
447.56
Type:
Small molecule
AlogP:
5.21
Polar Surface Area:
80.95
HBA:
6
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.41
Name:
1-(1-(4,5-dihydrothiazol-2-yl)-3-isopropyl-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea
Mol. Formula:
C18H23N5O2S2
M.W.:
405.55
Type:
Small molecule
AlogP:
3.63
Polar Surface Area:
80.42
HBA:
7
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.76