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Baculoviral IAP repeat-containing protein 3/Huntingtin
Name And Classification
ID: ALA4296121
Type: PROTEIN-PROTEIN INTERACTION
Synonyms: 2.3.2.27 | API2 | API2 | Apoptosis inhibitor 2 | Baculoviral IAP repeat-containing protein 3 | BIRC3 | C-IAP2 | Cellular inhibitor of apoptosis 2 | hIAP-1 | hIAP1 | IAP homolog C | Inhibitor of apoptosis protein 1 | MIHC | RING finger protein 49 | RING-type E3 ubiquitin transferase BIRC3 | RNF49 | TNFR2-TRAF-signaling complex protein 1
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Enzyme
Target Relations
ALA ID | Relationship | Pref Name | Target Type |
---|
ALA5514 | SUPERSET OF | Huntingtin | SINGLE PROTEIN |
ALA3038465 | OVERLAPS WITH | cIAP1/cIAP2 | PROTEIN FAMILY |
ALA5335 | SUPERSET OF | Baculoviral IAP repeat-containing protein 3 | SINGLE PROTEIN |
ALA3885522 | OVERLAPS WITH | Baculoviral IAP repeat-containing protein 3/Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | CHIMERIC PROTEIN |
Target Components
Description | Relationship | Accession |
Baculoviral IAP repeat-containing protein 3 | PROTEIN | Q13489 |
Huntingtin | PROTEIN | P42858 |
Associated Recombinant Proteins
Associated Active Ligands
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ALA4208207Name:
(S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-N-(2-(2-(2-(2-((4-(dimethylamino)phenyl)diazenyl)benzo[d]thiazol-6-yloxy)ethoxy)ethoxy)ethyl)-4-methylpentanamide
Mol. Formula:
C37H49N7O6S
M.W.:
719.91
Type:
Small molecule
AlogP:
4.77
Polar Surface Area:
172.99
HBA:
12
HBD:
4
#RO5 Violations:
2
#Rotatable Bonds:
21
Passes Ro3:
N
QED Weighted:
0.07
DETAILS
CLOSE
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ALA4213125Name:
(S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-4-methyl-N-(2-(2-(2-(4-(6-methylbenzo[d]thiazol-2-yl)phenylamino)ethoxy)ethoxy)ethyl)pentanamide
Mol. Formula:
C36H47N5O5S
M.W.:
661.87
Type:
Small molecule
AlogP:
4.29
Polar Surface Area:
147.83
HBA:
9
HBD:
5
#RO5 Violations:
1
#Rotatable Bonds:
19
Passes Ro3:
N
QED Weighted:
0.09
DETAILS
CLOSE
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ALA4217540Name:
(S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-N-((S)-1-(2-(2-(2-(2-((4-(dimethylamino)phenyl)diazenyl)benzo[d]thiazol-6-yloxy)ethoxy)ethoxy)ethylamino)-1-oxo-3,3-diphenylpropan-2-yl)pyrrolidine-2-carboxamide
Mol. Formula:
C53H67N9O7S
M.W.:
974.24
Type:
Small molecule
AlogP:
7.29
Polar Surface Area:
188.18
HBA:
13
HBD:
4
#RO5 Violations:
3
#Rotatable Bonds:
24
Passes Ro3:
N
QED Weighted:
0.04
DETAILS
CLOSE