Your company account is blocked and you cannot place orders. If you have questions, please contact your company administrator.

Melatonin receptor 1B

Name And Classification

ID:  ALA4466

Type:  SINGLE PROTEIN

Synonyms:   Mel-1B-R | Mel1b receptor | Melatonin receptor type 1B

Organism:  Gallus gallus

Species Group:  Gallus gallus

Protein Target Classification:   Membrane receptor / Family A G protein-coupled receptor / Small molecule receptor (family A GPCR) / Monoamine-derivative receptor (family A GPCR) / Melatonin receptor

Target Relations

ALA IDRelationshipPref NameTarget Type
ALA2095154SUBSET OFMelatonin receptorPROTEIN FAMILY

Target Components

DescriptionRelationshipAccession
Melatonin receptor type 1BPROTEINP51050

Associated Active Ligands

  1. Tetrahydrouridine
    ALA111558

    Name:
    1-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-pyrrolidin-2-one

    Mol. Formula:
    C17H19NO2

    M.W.:
    269.34

    Type:
    Small molecule

    AlogP:
    3.01

    Polar Surface Area:
    29.54

    HBA:
    2

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.85

    DETAILS
  2. Tetrahydrouridine
    ALA113067

    Name:
    N-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-acetamide

    Mol. Formula:
    C14H19NO2

    M.W.:
    233.31

    Type:
    Small molecule

    AlogP:
    2.25

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.87

    DETAILS
  3. Tetrahydrouridine
    ALA113243

    Name:
    N-(6-Methoxy-indan-1-ylmethyl)-butyramide

    Mol. Formula:
    C15H21NO2

    M.W.:
    247.34

    Type:
    Small molecule

    AlogP:
    2.64

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.87

    DETAILS
  4. Tetrahydrouridine
    ALA113244

    Name:
    N-(6-Methoxy-indan-1-ylmethyl)-propionamide

    Mol. Formula:
    C14H19NO2

    M.W.:
    233.31

    Type:
    Small molecule

    AlogP:
    2.25

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.87

    DETAILS
  5. Tetrahydrouridine
    ALA112164

    Name:
    N-(4-Methoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-ylmethyl)-butyramide

    Mol. Formula:
    C14H19NO2

    M.W.:
    233.31

    Type:
    Small molecule

    AlogP:
    2.25

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.85

    DETAILS
  6. Tetrahydrouridine
    ALA114929

    Name:
    N-(4-Methoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-ylmethyl)-propionamide

    Mol. Formula:
    C13H17NO2

    M.W.:
    219.28

    Type:
    Small molecule

    AlogP:
    1.86

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.84

    DETAILS
  7. Tetrahydrouridine
    ALA111667

    Name:
    N-(6-Methoxy-indan-1-ylmethyl)-acetamide

    Mol. Formula:
    C13H17NO2

    M.W.:
    219.28

    Type:
    Small molecule

    AlogP:
    1.86

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.84

    DETAILS
  8. Tetrahydrouridine
    ALA111866

    Name:
    N-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-butyramide

    Mol. Formula:
    C16H23NO2

    M.W.:
    261.36

    Type:
    Small molecule

    AlogP:
    3.03

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    5

    Passes Ro3:
    N

    QED Weighted:
    0.88

    DETAILS
  9. Tetrahydrouridine
    ALA419939

    Name:
    N-(4-Methoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-ylmethyl)-acetamide

    Mol. Formula:
    C12H15NO2

    M.W.:
    205.26

    Type:
    Small molecule

    AlogP:
    1.47

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    Y

    QED Weighted:
    0.81

    DETAILS
  10. Tetrahydrouridine
    ALA113859

    Name:
    N-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-propionamide

    Mol. Formula:
    C15H21NO2

    M.W.:
    247.34

    Type:
    Small molecule

    AlogP:
    2.64

    Polar Surface Area:
    38.33

    HBA:
    2

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.89

    DETAILS