ID: ALA4573
Type: SINGLE PROTEIN
Synonyms: GPRC1F | GRM6 | Metabotropic glutamate receptor 6 | MGLUR6 | mGluR6
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family C G protein-coupled receptor / Small molecule receptor (family C GPCR) / Neurotransmitter receptor (family C GPCR) / Metabotropic glutamate receptor
Description | Relationship | Accession |
---|---|---|
Metabotropic glutamate receptor 6 | PROTEIN | O15303 |
Name:
(S)-3-Methyl-1,2,3,4-tetrahydro-isoquinoline-3,6-dicarboxylic acid
Mol. Formula:
C12H13NO4
M.W.:
235.24
Type:
Small molecule
AlogP:
0.87
Polar Surface Area:
86.63
HBA:
3
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
2
Passes Ro3:
N
QED Weighted:
0.71
Name:
(S)-2-Amino-2-methyl-3-(3-phosphono-phenyl)-propionic acid
Mol. Formula:
C10H14NO5P
M.W.:
259.20
Type:
Small molecule
AlogP:
-0.17
Polar Surface Area:
120.85
HBA:
3
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.56
Name:
[((3S)-3-Amino-3-carboxy)propyl][(3-nitro-4-trifluoromethylphenyl)hydroxymethyl]phosphinic Acid
Mol. Formula:
C12H14F3N2O7P
M.W.:
386.22
Type:
Small molecule
AlogP:
1.68
Polar Surface Area:
163.99
HBA:
6
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.31
Name:
[((3S,1'S)-3-Amino-3-carboxy)propyl][(4-methoxy-3-nitrophenyl)hydroxymethyl]phosphinic Acid
Mol. Formula:
C12H17N2O8P
M.W.:
348.25
Type:
Small molecule
AlogP:
0.67
Polar Surface Area:
173.22
HBA:
7
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.30
Name:
[((3S,1'S)-3-Amino-3-carboxy)propyl][(4-hydroxy-3-nitrophenyl)hydroxymethyl]phosphinic Acid
Mol. Formula:
C11H15N2O8P
M.W.:
334.22
Type:
Small molecule
AlogP:
0.36
Polar Surface Area:
184.22
HBA:
7
HBD:
5
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.27
Name:
[((3S,1'S)-3-Amino-3-carboxy)propyl][(4-hydroxy-5-methoxy-3-nitrophenyl)hydroxymethyl]phosphinic Acid
Mol. Formula:
C12H17N2O9P
M.W.:
364.25
Type:
Small molecule
AlogP:
0.37
Polar Surface Area:
193.45
HBA:
8
HBD:
5
#RO5 Violations:
0
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.24
Name:
[((3S)-3-Amino-3-carboxy)propyl][(4-morpholino-3-nitrophenyl)hydroxymethyl]phosphinic Acid
Mol. Formula:
C15H22N3O8P
M.W.:
403.33
Type:
Small molecule
AlogP:
0.49
Polar Surface Area:
176.46
HBA:
8
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.27
Name:
[((3S)-3-Amino-3-carboxy)propyl][(4-hydroxy-3-nitrophenyl)methyl]phosphinic Acid
Mol. Formula:
C11H15N2O7P
M.W.:
318.22
Type:
Small molecule
AlogP:
0.87
Polar Surface Area:
163.99
HBA:
6
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.33
Name:
[((3S,1'R)-3-Amino-3-carboxy)propyl][(4-methoxy-3-nitrophenyl)hydroxymethyl]phosphinic Acid
Mol. Formula:
C12H17N2O8P
M.W.:
348.25
Type:
Small molecule
AlogP:
0.67
Polar Surface Area:
173.22
HBA:
7
HBD:
4
#RO5 Violations:
0
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.30
Name:
[((3S,1'R)-3-Amino-3-carboxy)propyl][(4-hydroxy-5-methoxy-3-nitrophenyl)hydroxymethyl]phosphinic Acid
Mol. Formula:
C12H17N2O9P
M.W.:
364.25
Type:
Small molecule
AlogP:
0.37
Polar Surface Area:
193.45
HBA:
8
HBD:
5
#RO5 Violations:
0
#Rotatable Bonds:
8
Passes Ro3:
N
QED Weighted:
0.24