ID: ALA4613
Type: SINGLE PROTEIN
Synonyms: B1 bradykinin receptor | B1bkr | B1R | Bdkrb1 | BK-1 receptor | Bkr | KB1 | Kinin B1 receptor
Organism: Rattus norvegicus
Species Group: Rattus norvegicus
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Peptide receptor (family A GPCR) / Short peptide receptor (family A GPCR) / Bradykinin receptor
Description | Relationship | Accession |
---|---|---|
B1 bradykinin receptor | PROTEIN | P97583 |
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
---|
Name:
1-(2-oxo-5-phenethyl-1-propyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-(4-(4-(pyridin-4-yl)piperazin-1-yl)phenyl)urea
Mol. Formula:
C36H39N7O2
M.W.:
601.76
Type:
Small molecule
AlogP:
5.73
Polar Surface Area:
93.17
HBA:
6
HBD:
2
#RO5 Violations:
2
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.26
Name:
(S)-2-{[(S)-1-((S)-2-{13-[(S)-2-((S)-2,6-Diamino-hexanoylamino)-5-guanidino-pentanoylamino]-tridecanoylamino}-3-hydroxy-propionyl)-pyrrolidine-2-carbonyl]-amino}-3-phenyl-propionic acid
Mol. Formula:
C42H72N10O8
M.W.:
845.10
Type:
Small molecule
AlogP:
0.67
Polar Surface Area:
310.68
HBA:
10
HBD:
10
#RO5 Violations:
2
#Rotatable Bonds:
32
Passes Ro3:
N
QED Weighted:
0.03
Name:
H-Lys-Arg-Gly-1-amino-1-carboxycyclododecane-Gly-Ser-Pro-Phe-OH
Mol. Formula:
C46H76N12O10
M.W.:
957.19
Type:
Protein
AlogP:
-1.35
Polar Surface Area:
368.88
HBA:
12
HBD:
12
#RO5 Violations:
3
#Rotatable Bonds:
25
Passes Ro3:
N
QED Weighted:
0.03
Name:
H-Lys-Arg-Gly-1-amino-1-carboxycyclononane-Gly-Ser-Pro-Phe-OH
Mol. Formula:
C43H70N12O10
M.W.:
915.11
Type:
Protein
AlogP:
-2.52
Polar Surface Area:
368.88
HBA:
12
HBD:
12
#RO5 Violations:
3
#Rotatable Bonds:
25
Passes Ro3:
N
QED Weighted:
0.03
Name:
H-Lys-Arg-1-amino-1-carboxycycloheptane-Ser-Pro-Phe-OH
Mol. Formula:
C37H60N10O8
M.W.:
772.95
Type:
Protein
AlogP:
-1.53
Polar Surface Area:
310.68
HBA:
10
HBD:
10
#RO5 Violations:
2
#Rotatable Bonds:
21
Passes Ro3:
N
QED Weighted:
0.03
Name:
H-Lys-Arg-Gly-1-amino-1-carboxycyclooctane-Gly-Ser-Pro-Phe-OH
Mol. Formula:
C42H68N12O10
M.W.:
901.08
Type:
Protein
AlogP:
-2.91
Polar Surface Area:
368.88
HBA:
12
HBD:
12
#RO5 Violations:
3
#Rotatable Bonds:
25
Passes Ro3:
N
QED Weighted:
0.03
Name:
H-Lys-Arg-Gly-1-amino-1-carboxycycloheptane-Gly-Ser-Pro-Phe-OH
Mol. Formula:
C41H66N12O10
M.W.:
887.05
Type:
Protein
AlogP:
-3.30
Polar Surface Area:
368.88
HBA:
12
HBD:
12
#RO5 Violations:
3
#Rotatable Bonds:
25
Passes Ro3:
N
QED Weighted:
0.02
Name:
H-Lys-Arg-Gly-1-amino-1-carboxycyclohexane-Gly-Ser-Pro-Phe-OH
Mol. Formula:
C40H64N12O10
M.W.:
873.03
Type:
Protein
AlogP:
-3.69
Polar Surface Area:
368.88
HBA:
12
HBD:
12
#RO5 Violations:
3
#Rotatable Bonds:
25
Passes Ro3:
N
QED Weighted:
0.03