ID: ALA4685
Type: SINGLE PROTEIN
Synonyms: 1.13.11.52 | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-dioxygenase 1 | Indoleamine-pyrrole 2,3-dioxygenase
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Enzyme / Oxidoreductase
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA4742272 | SUBSET OF | Cereblon/Indoleamine 2,3-dioxygenase 1 | PROTEIN-PROTEIN INTERACTION |
ALA5169061 | SUBSET OF | IDO1/VHL | PROTEIN-PROTEIN INTERACTION |
Description | Relationship | Accession |
---|---|---|
Indoleamine 2,3-dioxygenase 1 | PROTEIN | P14902 |
Name:
N-[2-(Indol-3-yl)ethyl]-S-[(naphth-2-yl)methyl]dithiocarbamate
Mol. Formula:
C22H20N2S2
M.W.:
376.55
Type:
Small molecule
AlogP:
5.67
Polar Surface Area:
27.82
HBA:
2
HBD:
2
#RO5 Violations:
1
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.44
Name:
N-[2-(Indol-3-yl)ethyl]-S-[(pyrid-3-yl)methyl]dithiocarbamate
Mol. Formula:
C17H17N3S2
M.W.:
327.48
Type:
Small molecule
AlogP:
3.91
Polar Surface Area:
40.71
HBA:
3
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.70
Name:
N-[2-(Indol-3-yl)ethyl]-S-[(pyrid-4-yl)methyl]dithiocarbamate
Mol. Formula:
C17H17N3S2
M.W.:
327.48
Type:
Small molecule
AlogP:
3.91
Polar Surface Area:
40.71
HBA:
3
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.70
Name:
N-[2-(Benzo[b]thiophen-3-yl)ethyl]-S-methyl-dithiocarbamate
Mol. Formula:
C12H13NS3
M.W.:
267.44
Type:
Small molecule
AlogP:
4.09
Polar Surface Area:
12.36
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.50