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Baculoviral IAP repeat-containing protein 2

Name And Classification

ID:  ALA5462

Type:  SINGLE PROTEIN

Synonyms:   2.3.2.27 | API1 | Baculoviral IAP repeat-containing protein 2 | BIRC2 | C-IAP1 | Cellular inhibitor of apoptosis 1 | hIAP-2 | hIAP2 | IAP homolog B | Inhibitor of apoptosis protein 2 | MIHB | RING finger protein 48 | RING-type E3 ubiquitin transferase BIRC2 | RNF48 | TNFR2-TRAF-signaling complex protein 2

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Enzyme

Target Relations

ALA IDRelationshipPref NameTarget Type
ALA4802032SUBSET OFBaculoviral IAP repeat-containing protein 2/Aldo-keto reductase family 1 member B1PROTEIN-PROTEIN INTERACTION
ALA2221342SUBSET OFComplex of retinoic acid binding (CRABPII) and inhibitor of apoptosis (cIAP1) proteinsPROTEIN COMPLEX
ALA4802031SUBSET OFBaculoviral IAP repeat-containing protein 2/Epidermal growth factor receptorPROTEIN-PROTEIN INTERACTION
ALA4680047SUBSET OFBaculoviral IAP repeat-containing protein 2/Hematopoietic prostaglandin D synthasePROTEIN-PROTEIN INTERACTION
ALA3038465SUBSET OFcIAP1/cIAP2PROTEIN FAMILY
ALA3885521SUBSET OFBaculoviral IAP repeat-containing protein 2/Estrogen receptorPROTEIN COMPLEX
ALA4630748SUBSET OFBaculoviral IAP repeat-containing protein 2/Cyclin-dependent kinase 4PROTEIN-PROTEIN INTERACTION
ALA4296118SUBSET OFAndrogen receptor/Baculoviral IAP repeat-containing protein 2PROTEIN-PROTEIN INTERACTION
ALA4630749SUBSET OFBaculoviral IAP repeat-containing protein 2/Cyclin-dependent kinase 6PROTEIN-PROTEIN INTERACTION
ALA4802030SUBSET OFBaculoviral IAP repeat-containing protein 2/Prostaglandin E synthasePROTEIN-PROTEIN INTERACTION

Target Components

DescriptionRelationshipAccession
Baculoviral IAP repeat-containing protein 2PROTEINQ13490

Associated Active Ligands

  1. Tetrahydrouridine
    ALA457093

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-pentylpropanoyl]-L-leucine methyl ester

    Mol. Formula:
    C16H30N2O5

    M.W.:
    330.43

    Type:
    Small molecule

    AlogP:
    1.78

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    11

    Passes Ro3:
    N

    QED Weighted:
    0.23

    DETAILS
  2. Tetrahydrouridine
    ALA457466

    Name:
    N-[(S)-3-Hydroxycarbamoyl-2-pentylpropanoyl]-L-leucine methyl ester

    Mol. Formula:
    C16H30N2O5

    M.W.:
    330.43

    Type:
    Small molecule

    AlogP:
    1.78

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    11

    Passes Ro3:
    N

    QED Weighted:
    0.23

    DETAILS
  3. Tetrahydrouridine
    ALA458563

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-ethylpropanoyl]-L-leucine methyl ester

    Mol. Formula:
    C13H24N2O5

    M.W.:
    288.34

    Type:
    Small molecule

    AlogP:
    0.61

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    8

    Passes Ro3:
    N

    QED Weighted:
    0.34

    DETAILS
  4. Tetrahydrouridine
    ALA458564

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-benzylpropanyl]-L-leucine methyl ester

    Mol. Formula:
    C18H26N2O5

    M.W.:
    350.42

    Type:
    Small molecule

    AlogP:
    1.44

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.36

    DETAILS
  5. Tetrahydrouridine
    ALA457291

    Name:
    N-[N-Hydroxysuccinamiyl]-L-leucine methylester

    Mol. Formula:
    C11H20N2O5

    M.W.:
    260.29

    Type:
    Small molecule

    AlogP:
    -0.02

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.34

    DETAILS
  6. Tetrahydrouridine
    ALA457060

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-pentylpropanoyl]glycine methyl ester

    Mol. Formula:
    C12H22N2O5

    M.W.:
    274.32

    Type:
    Small molecule

    AlogP:
    0.37

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  7. Tetrahydrouridine
    ALA457292

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-pentylpropanoyl]-L-alanine methyl ester

    Mol. Formula:
    C13H24N2O5

    M.W.:
    288.34

    Type:
    Small molecule

    AlogP:
    0.76

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.25

    DETAILS
  8. Tetrahydrouridine
    ALA457293

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-pentylpropanoyl]-L-valine methyl ester

    Mol. Formula:
    C15H28N2O5

    M.W.:
    316.40

    Type:
    Small molecule

    AlogP:
    1.39

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    10

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS
  9. Tetrahydrouridine
    ALA458586

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-pentylpropanoyl]-L-tert-leucine methyl ester

    Mol. Formula:
    C16H30N2O5

    M.W.:
    330.43

    Type:
    Small molecule

    AlogP:
    1.78

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    9

    Passes Ro3:
    N

    QED Weighted:
    0.26

    DETAILS
  10. Tetrahydrouridine
    ALA458592

    Name:
    N-[(R)-3-Hydroxycarbamoyl-2-pentylpropanoyl]-L-phenylalanine methyl ester

    Mol. Formula:
    C19H28N2O5

    M.W.:
    364.44

    Type:
    Small molecule

    AlogP:
    1.98

    Polar Surface Area:
    104.73

    HBA:
    5

    HBD:
    3

    #RO5 Violations:
    0

    #Rotatable Bonds:
    11

    Passes Ro3:
    N

    QED Weighted:
    0.24

    DETAILS