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Baculoviral IAP repeat-containing protein 5

Name And Classification

ID:  ALA5989

Type:  SINGLE PROTEIN

Synonyms:   API4 | Apoptosis inhibitor 4 | Apoptosis inhibitor survivin | Baculoviral IAP repeat-containing protein 5 | BIRC5 | IAP4

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Unclassified protein

Target Components

DescriptionRelationshipAccession
Baculoviral IAP repeat-containing protein 5PROTEINO15392

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Active Ligands

  1. Tetrahydrouridine
    ALA391586

    Name:
    6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile

    Mol. Formula:
    C18H11BrN2O2

    M.W.:
    367.20

    Type:
    Small molecule

    AlogP:
    4.05

    Polar Surface Area:
    76.88

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.72

    DETAILS
  2. Tetrahydrouridine
    ALA233218

    Name:
    1-(4-chlorophenyl)-1H-indole

    Mol. Formula:
    C14H10ClN

    M.W.:
    227.69

    Type:
    Small molecule

    AlogP:
    4.28

    Polar Surface Area:
    4.93

    HBA:
    1

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.58

    DETAILS
  3. Tetrahydrouridine
    ALA395633

    Name:
    N-(3-chlorophenyl)naphthalen-2-amine

    Mol. Formula:
    C16H12ClN

    M.W.:
    253.73

    Type:
    Small molecule

    AlogP:
    5.24

    Polar Surface Area:
    12.03

    HBA:
    1

    HBD:
    1

    #RO5 Violations:
    1

    #Rotatable Bonds:
    2

    Passes Ro3:
    N

    QED Weighted:
    0.66

    DETAILS
  4. Tetrahydrouridine
    ALA232200

    Name:
    3-[2-[(Z)-hydroxyimino]-3-(4'-trifluoromethoxy-biphenyl-4-yloxy)-propyl]-5,5-dimethyl-imidazolidine-2,4-dione

    Mol. Formula:
    C21H20F3N3O5

    M.W.:
    451.40

    Type:
    Small molecule

    AlogP:
    3.79

    Polar Surface Area:
    100.46

    HBA:
    6

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    7

    Passes Ro3:
    N

    QED Weighted:
    0.29

    DETAILS
  5. Tetrahydrouridine
    ALA397092

    Name:
    3-(3-bromophenyl)quinoline

    Mol. Formula:
    C15H10BrN

    M.W.:
    284.16

    Type:
    Small molecule

    AlogP:
    4.66

    Polar Surface Area:
    12.89

    HBA:
    1

    HBD:
    0

    #RO5 Violations:
    0

    #Rotatable Bonds:
    1

    Passes Ro3:
    N

    QED Weighted:
    0.63

    DETAILS
  6. Tetrahydrouridine
    ALA232201

    Name:
    (2-ethylbenzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone

    Mol. Formula:
    C17H12I2O3

    M.W.:
    518.09

    Type:
    Small molecule

    AlogP:
    5.14

    Polar Surface Area:
    50.44

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    2

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.39

    DETAILS
  7. Tetrahydrouridine
    ALA277554

    Name:
    N-(4-methylpyridin-2-yl)piperidine-4-carboxamide

    Mol. Formula:
    C12H17N3O

    M.W.:
    219.29

    Type:
    Small molecule

    AlogP:
    1.33

    Polar Surface Area:
    54.02

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    Y

    QED Weighted:
    0.79

    DETAILS
  8. Tetrahydrouridine
    ALA391106

    Name:
    4-(2,5-dichloro-phenyl)-6-(4-hydroxy-biphenyl-3-yl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile

    Mol. Formula:
    C24H14Cl2N2O2

    M.W.:
    433.29

    Type:
    Small molecule

    AlogP:
    6.26

    Polar Surface Area:
    76.88

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.40

    DETAILS
  9. Tetrahydrouridine
    ALA232402

    Name:
    6-(5-cyclopentyl-2-hydroxyphenyl)-4-(2,5-dichlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile

    Mol. Formula:
    C23H18Cl2N2O2

    M.W.:
    425.32

    Type:
    Small molecule

    AlogP:
    6.25

    Polar Surface Area:
    76.88

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.52

    DETAILS
  10. Tetrahydrouridine
    ALA399196

    Name:
    4-(2,5-dichlorophenyl)-6-(2-hydroxy-5-isobutylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile

    Mol. Formula:
    C22H18Cl2N2O2

    M.W.:
    413.30

    Type:
    Small molecule

    AlogP:
    5.79

    Polar Surface Area:
    76.88

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    1

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.57

    DETAILS