ID: ALA6032
Type: SINGLE PROTEIN
Synonyms: 2.1.1.- | 2.1.1.367 | BAT8 | C6orf30 | EHMT2 | Euchromatic histone-lysine N-methyltransferase 2 | G9A | H3-K9-HMTase 3 | Histone H3-K9 methyltransferase 3 | Histone-lysine N-methyltransferase EHMT2 | HLA-B-associated transcript 8 | KMT1C | Lysine N-methyltransferase 1C | NG36 | Protein G9a
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Epigenetic regulator / Writer / Protein methyltransferase
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA3885593 | SUBSET OF | Histone-lysine N-methyltransferase EHMT1/EHMT2 | PROTEIN FAMILY |
Description | Relationship | Accession |
---|---|---|
Histone-lysine N-methyltransferase EHMT2 | PROTEIN | Q96KQ7 |
Name:
7-(3-(dimethylamino)propoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Mol. Formula:
C26H43N7O2
M.W.:
485.68
Type:
Small molecule
AlogP:
2.62
Polar Surface Area:
69.23
HBA:
9
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
9
Passes Ro3:
N
QED Weighted:
0.54
Name:
6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(tetrahydro-2H-pyran-4-yl)quinazolin-4-amine
Mol. Formula:
C21H31N5O3
M.W.:
401.51
Type:
Small molecule
AlogP:
2.38
Polar Surface Area:
71.98
HBA:
8
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.82
Name:
6,7-dimethoxy-N-(1-methylpiperidin-4-yl)-2-morpholinoquinazolin-4-amine
Mol. Formula:
C20H29N5O3
M.W.:
387.48
Type:
Small molecule
AlogP:
1.99
Polar Surface Area:
71.98
HBA:
8
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.84
Name:
N2,N2-diethyl-6,7-dimethoxy-N4-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
Mol. Formula:
C20H31N5O2
M.W.:
373.50
Type:
Small molecule
AlogP:
3.00
Polar Surface Area:
62.75
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.80
Name:
N-cyclohexyl-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Mol. Formula:
C22H33N5O2
M.W.:
399.54
Type:
Small molecule
AlogP:
3.53
Polar Surface Area:
62.75
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.83
Name:
N-cyclopropyl-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine
Mol. Formula:
C19H27N5O2
M.W.:
357.46
Type:
Small molecule
AlogP:
2.36
Polar Surface Area:
62.75
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.88
Name:
6,7-dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine
Mol. Formula:
C18H27N5O2
M.W.:
345.45
Type:
Small molecule
AlogP:
2.22
Polar Surface Area:
62.75
HBA:
7
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.89