Your company account is blocked and you cannot place orders. If you have questions, please contact your company administrator.

Detroit 551

Name And Classification

ID:  ALA614284

Type:  CELL-LINE

Organism:  Homo sapiens

Species Group:  Homo sapiens

Name:  Detroit 551

Description:  Detroit 551

Source tissue:  Embryonic skin

Source Organism:  Homo sapiens

Source Tax ID:  9606

Cell Line Ontology:  CLO_0002751

Cellosaurus:  CVCL_2434

Target Relations

ALA IDRelationshipPref NameTarget Type

Associated Active Ligands

  1. Tetrahydrouridine
    ALA2313574

    Name:
    3'-dimethylamino-6-pyrrolinyl-2-phenyl-4-quinolone

    Mol. Formula:
    C21H23N3O

    M.W.:
    333.44

    Type:
    Small molecule

    AlogP:
    3.86

    Polar Surface Area:
    39.34

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.79

    DETAILS
  2. Tetrahydrouridine
    ALA2313575

    Name:
    3'-ethylamino-6-pyrrolinyl-2-phenyl-4-quinolone

    Mol. Formula:
    C21H23N3O

    M.W.:
    333.44

    Type:
    Small molecule

    AlogP:
    4.23

    Polar Surface Area:
    48.13

    HBA:
    3

    HBD:
    2

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.75

    DETAILS
  3. Tetrahydrouridine
    ALA2413503

    Name:
    4-Ethyl-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C13H13NO2

    M.W.:
    215.25

    Type:
    Small molecule

    AlogP:
    2.90

    Polar Surface Area:
    38.30

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    2

    Passes Ro3:
    Y

    QED Weighted:
    0.71

    DETAILS
  4. Tetrahydrouridine
    ALA2413505

    Name:
    4-(2-Fluorobenzyl)-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C18H14FNO2

    M.W.:
    295.31

    Type:
    Small molecule

    AlogP:
    4.07

    Polar Surface Area:
    38.30

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  5. Tetrahydrouridine
    ALA2413506

    Name:
    4-(3-Fluorobenzyl)-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C18H14FNO2

    M.W.:
    295.31

    Type:
    Small molecule

    AlogP:
    4.07

    Polar Surface Area:
    38.30

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  6. Tetrahydrouridine
    ALA2413507

    Name:
    4-(4-Fluorobenzyl)-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C18H14FNO2

    M.W.:
    295.31

    Type:
    Small molecule

    AlogP:
    4.07

    Polar Surface Area:
    38.30

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS
  7. Tetrahydrouridine
    ALA2413508

    Name:
    4-(2-Chlorobenzyl)-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C18H14ClNO2

    M.W.:
    311.77

    Type:
    Small molecule

    AlogP:
    4.58

    Polar Surface Area:
    38.30

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  8. Tetrahydrouridine
    ALA2413617

    Name:
    4-(3-Chlorobenzyl)-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C18H14ClNO2

    M.W.:
    311.77

    Type:
    Small molecule

    AlogP:
    4.58

    Polar Surface Area:
    38.30

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  9. Tetrahydrouridine
    ALA2413618

    Name:
    4-(4-Chlorobenzyl)-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C18H14ClNO2

    M.W.:
    311.77

    Type:
    Small molecule

    AlogP:
    4.58

    Polar Surface Area:
    38.30

    HBA:
    3

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    3

    Passes Ro3:
    N

    QED Weighted:
    0.60

    DETAILS
  10. Tetrahydrouridine
    ALA2413619

    Name:
    4-(2-Methoxybenzyl)-4H-furo[3,2-b]indole-2-methanol

    Mol. Formula:
    C19H17NO3

    M.W.:
    307.35

    Type:
    Small molecule

    AlogP:
    3.94

    Polar Surface Area:
    47.53

    HBA:
    4

    HBD:
    1

    #RO5 Violations:
    0

    #Rotatable Bonds:
    4

    Passes Ro3:
    N

    QED Weighted:
    0.62

    DETAILS