# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1614701 | AZD-6244 | IC50 | = | 0.95 | uM | ALA5226853 | 6.02 | nM | Homo sapiens | ||
2. | ALA1614701 | AZD-6244 | IC50 | = | 1.25 | uM | ALA5226852 | 5.90 | nM | Homo sapiens | ||
3. | ALA1614701 | AZD-6244 | Kd | = | 530 | nM | ALA5213094 | 6.28 | nM | Homo sapiens | ||
4. | ALA1614701 | AZD-6244 | Kd | = | 99 | nM | ALA5213093 | 7.00 | nM | Homo sapiens | ||
5. | ALA1614701 | AZD-6244 | Kd | = | 530 | nM | ALA5210362 | 6.28 | nM | Homo sapiens | ||
6. | ALA1614701 | AZD-6244 | Kd | = | 99 | nM | ALA5210361 | 7.00 | nM | Homo sapiens | ||
7. | ALA1614701 | AZD-6244 | IC50 | = | 14 | nM | ALA5210136 | 7.85 | nM | Homo sapiens | ||
8. | ALA1614701 | AZD-6244 | IC50 | = | 14 | nM | ALA5131972 | 7.85 | nM | Homo sapiens | ||
9. | ALA1614701 | AZD-6244 | Activity | > | 95 | % | ALA5131931 | % | Middle East respiratory syndrome-related coronavirus | |||
10. | ALA1614701 | AZD-6244 | EC50 | = | 0.75 | uM | ALA5131834 | 6.12 | nM | Influenza A virus | ||
11. | ALA1614701 | AZD-6244 | IC50 | = | 14 | nM | ALA5131810 | 7.85 | nM | |||
12. | ALA1614701 | AZD-6244 | CC50 | > | 100 | uM | ALA5131791 | nM | Homo sapiens | |||
13. | ALA1614701 | AZD-6244 | EC50 | = | 0.75 | uM | ALA5131622 | 6.12 | nM | Influenza A virus | ||
14. | ALA1614701 | AZD-6244 | Kd | = | 0.014 | uM | ALA5122292 | 7.85 | nM | |||
15. | ALA1614701 | AZD-6244 | TGI | = | 49 | % | ALA4422711 | % | Homo sapiens | |||
16. | ALA1614701 | AZD-6244 | INH | 0 | ALA4370949 | Not Active | % | |||||
17. | ALA1614701 | AZD-6244 | INH | = | 65 | % | ALA4370948 | % | ||||
18. | ALA1614701 | AZD-6244 | IC50 | > | 100 | uM | ALA4370938 | nM | Homo sapiens | |||
19. | ALA1614701 | AZD-6244 | IC50 | = | 14 | nM | ALA4729702 | 7.85 | nM | Homo sapiens | ||
20. | ALA1614701 | AZD-6244 | Growth Rate | = | 1 | ALA4725213 | Homo sapiens |