| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | CL | = | 5.2 | mL/min/kg | ALA1614677 | mL.min-1.kg-1 | ||||
| 2. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | CL | = | 3.2 | mL/min/kg | ALA1614679 | mL.min-1.kg-1 | ||||
| 3. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | Vdss | = | 1.8 | L/kg | ALA1614680 | L.kg-1 | ||||
| 4. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | Vdss | = | 1.4 | mL/min/kg | ALA1614676 | mL/min/kg | ||||
| 5. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | Vdss | = | 0.63 | L/kg | ALA1614678 | L.kg-1 | ||||
| 6. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | CL | = | 0.34 | mL/min/kg | ALA1614681 | mL.min-1.kg-1 | ||||
| 7. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | Vdss | = | 0.24 | L/kg | ALA1614682 | L.kg-1 | ||||
| 8. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | CL | = | 52 | mL/min/kg | ALA1614675 | mL.min-1.kg-1 | ||||
| 9. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | E max | = | 100 | % | ALA675474 | % | Homo sapiens | |||
| 10. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | EC50 | = | 0.08 | nM | ALA676117 | 10.10 | nM | Homo sapiens | ||
| 11. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | IC50 | = | 2.9 | nM | ALA677098 | 8.54 | nM | Homo sapiens | ||
| 12. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | RBA | = | 15.3 | % | ALA678563 | % | Rattus norvegicus | |||
| 13. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | RBA | = | 15.3 | ALA676227 | Mus musculus | |||||
| 14. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | RBA | = | 185 | ALA678830 | Ovis aries | |||||
| 15. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | RBA | = | 14 | ALA678829 | Ovis aries | |||||
| 16. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | Emax | = | 100 | % | ALA639915 | % | Homo sapiens | |||
| 17. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | EC50 | = | 0.1 | nM | ALA639914 | 10.00 | nM | Homo sapiens | ||
| 18. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | IC50 | = | 2.5 | nM | ALA677101 | 8.60 | nM | Homo sapiens | ||
| 19. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | Ratio | = | 0.4 | ALA850511 | ||||||
| 20. | ALA1628161 | 17-alpha-ethynyl-11-beta-methoxyestradiol | Antifertility potency | = | 1000 | ALA774150 | Rattus norvegicus |
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