| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA303933 | PQ(Piperaquine) | IC50 | = | 0.045 | uM | ALA4481289 | 7.34 | nM | Plasmodium vivax | ||
| 2. | ALA303933 | PQ(Piperaquine) | IC50 | = | 0.021 | uM | ALA4481288 | 7.68 | nM | Plasmodium falciparum | ||
| 3. | ALA303933 | PQ(Piperaquine) | IC50 | = | 0.051 | uM | ALA4481287 | 7.29 | nM | Plasmodium falciparum | ||
| 4. | ALA303933 | PQ(Piperaquine) | IC50 | = | 0.039 | uM | ALA4481286 | 7.42 | nM | Plasmodium falciparum | ||
| 5. | ALA303933 | PQ(Piperaquine) | inhibition | = | -8.35 | % | ALA4808150 | % | Homo sapiens | |||
| 6. | ALA303933 | PQ(Piperaquine) | inhibition | = | -20.41 | % | ALA4808149 | % | Homo sapiens | |||
| 7. | ALA303933 | PQ(Piperaquine) | IC50 | = | 81.3 | nM | ALA4683335 | 7.09 | nM | Plasmodium falciparum | ||
| 8. | ALA303933 | PQ(Piperaquine) | INH | 0 | ALA4392013 | Not Active | % | |||||
| 9. | ALA303933 | PQ(Piperaquine) | IC50 | = | 5 | nM | ALA4392008 | 8.30 | nM | Plasmodium falciparum | ||
| 10. | ALA303933 | PQ(Piperaquine) | IC50 | = | 7.2 | nM | ALA4392007 | 8.14 | nM | Plasmodium falciparum | ||
| 11. | ALA303933 | PQ(Piperaquine) | IC50 | = | 10 | nM | ALA4392006 | 8.00 | nM | Plasmodium falciparum | ||
| 12. | ALA303933 | PQ(Piperaquine) | IC50 | = | 7.4 | nM | ALA4392005 | 8.13 | nM | Plasmodium falciparum | ||
| 13. | ALA303933 | PQ(Piperaquine) | IC50 | = | 7.1 | nM | ALA4392004 | 8.15 | nM | Plasmodium falciparum | ||
| 14. | ALA303933 | PQ(Piperaquine) | IC50 | = | 9 | nM | ALA4391970 | 8.05 | nM | Plasmodium falciparum | ||
| 15. | ALA303933 | PQ(Piperaquine) | Activity | = | 79.2 | % | ALA4378092 | % | ||||
| 16. | ALA303933 | PQ(Piperaquine) | Ki | = | 90 | nM | ALA4378090 | 7.05 | nM | Homo sapiens | ||
| 17. | ALA303933 | PQ(Piperaquine) | Ratio AUC | = | 21 | ALA4606302 | ||||||
| 18. | ALA303933 | PQ(Piperaquine) | IC50 | = | 5.9 | nM | ALA4606282 | 8.23 | nM | Plasmodium falciparum | ||
| 19. | ALA303933 | PQ(Piperaquine) | AC50 | > | 30 | uM | ALA5291746 | Summarised AC50 (mean value for measurements with a relation sign "="; largest value for measurements with relation sign ">") | nM | Rattus norvegicus | ||
| 20. | ALA303933 | PQ(Piperaquine) | AC50 | > | 30 | uM | ALA5291747 | Summarised AC50 (mean value for measurements with a relation sign "="; largest value for measurements with relation sign ">") | nM | Rattus norvegicus |
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