# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1642546 | 9 | IC50 | = | 3.5 | uM | ALA1924375 | 5.46 | nM | Homo sapiens | ||
2. | ALA1642546 | 9 | IC50 | = | 0.22 | uM | ALA1924374 | 6.66 | nM | Homo sapiens | ||
3. | ALA1642546 | 9 | IC50 | = | 19 | nM | ALA1924373 | 7.72 | nM | Homo sapiens | ||
4. | ALA1642546 | 9 | INH | 0 | ALA1646103 | Dose-dependent effect | % | Mus musculus | ||||
5. | ALA1642546 | 9 | INH | = | 75 | % | ALA1646313 | % | Mus musculus | |||
6. | ALA1642546 | 9 | INH | = | 80 | % | ALA1646314 | % | Mus musculus | |||
7. | ALA1642546 | 9 | AUC | = | 1980 | nM | ALA1646289 | nM | Canis lupus familiaris | |||
8. | ALA1642546 | 9 | AUC | = | 4630 | nM | ALA1646290 | nM | Rattus norvegicus | |||
9. | ALA1642546 | 9 | AUC | = | 3000 | nM | ALA1646291 | nM | Mus musculus | |||
10. | ALA1642546 | 9 | Vdss | = | 3.1 | L/Kg | ALA1646292 | L.kg-1 | Canis lupus familiaris | |||
11. | ALA1642546 | 9 | Vdss | = | 2.3 | L/Kg | ALA1646293 | L.kg-1 | Rattus norvegicus | |||
12. | ALA1642546 | 9 | Vdss | = | 1.5 | L/Kg | ALA1646294 | L.kg-1 | Mus musculus | |||
13. | ALA1642546 | 9 | CL | = | 43 | ml/min.kg | ALA1646295 | mL.min-1.kg-1 | Canis lupus familiaris | |||
14. | ALA1642546 | 9 | CL | = | 63 | ml/min.kg | ALA1646298 | mL.min-1.kg-1 | Rattus norvegicus | |||
15. | ALA1642546 | 9 | CL | = | 62 | ml/min.kg | ALA1646297 | mL.min-1.kg-1 | Mus musculus | |||
16. | ALA1642546 | 9 | MRT | = | 2.1 | hr | ALA1646299 | hr | Rattus norvegicus | |||
17. | ALA1642546 | 9 | MRT | = | 2.9 | hr | ALA1646300 | hr | Mus musculus | |||
18. | ALA1642546 | 9 | t1/2 | = | 0.7 | hr | ALA1646301 | hr | Canis lupus familiaris | |||
19. | ALA1642546 | 9 | t1/2 | = | 0.6 | hr | ALA1646303 | hr | Rattus norvegicus | |||
20. | ALA1642546 | 9 | t1/2 | = | 1.9 | hr | ALA1646302 | hr | Mus musculus |