# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1651866 | NPC1161B | IC50 | < | 1 | uM | ALA2433135 | nM | Plasmodium yoelii | |||
2. | ALA1651866 | NPC1161B | INH | = | 50 | % | ALA2433134 | % | Plasmodium falciparum | |||
3. | ALA1651866 | NPC1161B | IC50 | = | 3.8 | uM | ALA2184957 | 5.42 | nM | Plasmodium falciparum | ||
4. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656236 | Not Active | Plasmodium berghei | |||||
5. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656218 | Active | Pneumocystis carinii | |||||
6. | ALA1651866 | NPC1161B | ED90 | = | 3.61 | mg Kg-1 | ALA1656224 | mg Kg-1 | Leishmania donovani | |||
7. | ALA1651866 | NPC1161B | ED50 | = | 1.28 | mg Kg-1 | ALA1656224 | mg.kg-1 | Leishmania donovani | |||
8. | ALA1651866 | NPC1161B | INH | = | 61.49 | % | ALA1657561 | % | Leishmania donovani | |||
9. | ALA1651866 | NPC1161B | INH | = | 98 | % | ALA1657560 | % | Leishmania donovani | |||
10. | ALA1651866 | NPC1161B | INH | = | 99.29 | % | ALA1657559 | % | Leishmania donovani | |||
11. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656220 | Active | Pneumocystis carinii | |||||
12. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656219 | Active | Pneumocystis carinii | |||||
13. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656217 | Active | Pneumocystis carinii | |||||
14. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656215 | Active | Pneumocystis carinii | |||||
15. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656059 | Active | Pneumocystis carinii | |||||
16. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656058 | Active | Pneumocystis carinii | |||||
17. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656057 | Active | Pneumocystis carinii | |||||
18. | ALA1651866 | NPC1161B | Activity | 0 | ALA1656055 | Active | Pneumocystis carinii | |||||
19. | ALA1651866 | NPC1161B | INH | = | 99.8 | % | ALA1656034 | % | Leishmania donovani | |||
20. | ALA1651866 | NPC1161B | MST | = | 8.4 | day | ALA1656038 | day | Plasmodium berghei |