| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1652588 | E | pKa_B1 | 0 | ALA3301362 | "B1 Functional Group: 1H-imidazole, 1-methyl-; Ionisation Formula: A0B2 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 2. | ALA1652588 | E | LogD7.4 | 3.16 | ALA3301363 | |||||||
| 3. | ALA1652588 | E | F | = | 100 | % | ALA2092133 | % | Mus musculus | |||
| 4. | ALA1652588 | E | FC | = | 1 | ALA2092130 | Helicobacter pylori | |||||
| 5. | ALA1652588 | E | pKa | = | 7.2 | ALA2092129 | ||||||
| 6. | ALA1652588 | E | PPB | = | 4 | % | ALA2092128 | % | Mus musculus | |||
| 7. | ALA1652588 | E | Vdss | = | 3.6 | L/Kg | ALA2092127 | L.kg-1 | Mus musculus | |||
| 8. | ALA1652588 | E | t1/2 | = | 2.1 | hr | ALA2092126 | hr | Mus musculus | |||
| 9. | ALA1652588 | E | CL | = | 20 | ml/min.kg | ALA2092125 | mL.min-1.kg-1 | Mus musculus | |||
| 10. | ALA1652588 | E | CLH | = | 18 | uL/min | ALA2092120 | uL/min | Mus musculus | |||
| 11. | ALA1652588 | E | CLH | < | 14 | uL/min | ALA2092119 | uL/min | Homo sapiens | |||
| 12. | ALA1652588 | E | MIC | = | 0.5 | ug ml-1 | ALA2092118 | ug.mL-1 | Helicobacter pylori | |||
| 13. | ALA1652588 | E | MIC | = | 2 | ug ml-1 | ALA2092117 | ug.mL-1 | Helicobacter pylori | |||
| 14. | ALA1652588 | E | IC50 | = | 24 | nM | ALA2092116 | 7.62 | nM | Helicobacter pylori J99 | ||
| 15. | ALA1652588 | E | MIC | > | 64 | ug ml-1 | ALA1655029 | ug.mL-1 | Staphylococcus aureus | |||
| 16. | ALA1652588 | E | MIC | > | 64 | ug ml-1 | ALA1655028 | ug.mL-1 | Escherichia coli | |||
| 17. | ALA1652588 | E | MIC | = | 0.25 | ug ml-1 | ALA1655027 | ug.mL-1 | Helicobacter pylori | |||
| 18. | ALA1652588 | E | MIC | = | 8 | ug ml-1 | ALA1655026 | ug.mL-1 | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) | |||
| 19. | ALA1652588 | E | MIC | = | 1 | ug ml-1 | ALA1655025 | ug.mL-1 | Helicobacter pylori | |||
| 20. | ALA1652588 | E | MIC | = | 2 | ug ml-1 | ALA1655024 | ug.mL-1 | Helicobacter pylori |
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