# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1684573 | 12i | Stability | = | 65 | % | ALA1686966 | % | Rattus norvegicus | |||
2. | ALA1684573 | 12i | F | = | 55 | % | ALA1686977 | % | Rattus norvegicus | |||
3. | ALA1684573 | 12i | AUC | = | 515 | ng/mL.hr | ALA1686976 | ng.hr.mL-1 | Rattus norvegicus | |||
4. | ALA1684573 | 12i | AUC | = | 759 | ng/mL.hr | ALA1686975 | ng.hr.mL-1 | Rattus norvegicus | |||
5. | ALA1684573 | 12i | Vdss | = | 3.9 | L/Kg | ALA1686974 | L.kg-1 | Rattus norvegicus | |||
6. | ALA1684573 | 12i | beta t1/2 | = | 1.2 | hr | ALA1686973 | hr | Rattus norvegicus | |||
7. | ALA1684573 | 12i | CL | = | 43 | ml/min.kg | ALA1686972 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA1684573 | 12i | IC50 | > | 100000 | nM | ALA1686971 | nM | Homo sapiens | |||
9. | ALA1684573 | 12i | IC50 | > | 100000 | nM | ALA1686970 | nM | Homo sapiens | |||
10. | ALA1684573 | 12i | IC50 | > | 100000 | nM | ALA1686969 | nM | Homo sapiens | |||
11. | ALA1684573 | 12i | IC50 | = | 2 | nM | ALA1686968 | 8.70 | nM | Rattus norvegicus | ||
12. | ALA1684573 | 12i | IC50 | = | 3 | nM | ALA1686967 | 8.52 | nM | Homo sapiens | ||
13. | ALA1684573 | 12i | Stability | = | 67 | % | ALA1686965 | % | Homo sapiens | |||
14. | ALA1684573 | 12i | IC50 | = | 3 | nM | ALA1686964 | 8.52 | nM | Homo sapiens |