| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1684574 | 12j | t1/2 | = | 11.5 | hr | ALA1686984 | hr | Homo sapiens | |||
| 2. | ALA1684574 | 12j | Tmax | = | 3 | hr | ALA1686983 | hr | Homo sapiens | |||
| 3. | ALA1684574 | 12j | AUC | = | 1013 | ng.hr/ml | ALA1686982 | ng.hr.mL-1 | Homo sapiens | |||
| 4. | ALA1684574 | 12j | Cmax | = | 79 | ng/ml | ALA1686981 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Homo sapiens | ||
| 5. | ALA1684574 | 12j | Activity | 0 | ALA1686980 | Active | Rattus norvegicus | |||||
| 6. | ALA1684574 | 12j | Activity | 0 | ALA1686979 | Dose-dependent effect | Rattus norvegicus | |||||
| 7. | ALA1684574 | 12j | IC50 | > | 30 | uM | ALA1686978 | nM | ||||
| 8. | ALA1684574 | 12j | F | = | 53 | % | ALA1686977 | % | Rattus norvegicus | |||
| 9. | ALA1684574 | 12j | AUC | = | 2565 | ng/mL.hr | ALA1686976 | ng.hr.mL-1 | Rattus norvegicus | |||
| 10. | ALA1684574 | 12j | AUC | = | 980 | ng/mL.hr | ALA1686975 | ng.hr.mL-1 | Rattus norvegicus | |||
| 11. | ALA1684574 | 12j | Vdss | = | 9.7 | L/Kg | ALA1686974 | L.kg-1 | Rattus norvegicus | |||
| 12. | ALA1684574 | 12j | beta t1/2 | = | 3.8 | hr | ALA1686973 | hr | Rattus norvegicus | |||
| 13. | ALA1684574 | 12j | CL | = | 36.3 | ml/min.kg | ALA1686972 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 14. | ALA1684574 | 12j | IC50 | > | 100000 | nM | ALA1686971 | nM | Homo sapiens | |||
| 15. | ALA1684574 | 12j | IC50 | > | 100000 | nM | ALA1686970 | nM | Homo sapiens | |||
| 16. | ALA1684574 | 12j | IC50 | > | 100000 | nM | ALA1686969 | nM | Homo sapiens | |||
| 17. | ALA1684574 | 12j | IC50 | = | 4 | nM | ALA1686968 | 8.40 | nM | Rattus norvegicus | ||
| 18. | ALA1684574 | 12j | IC50 | = | 6 | nM | ALA1686967 | 8.22 | nM | Homo sapiens | ||
| 19. | ALA1684574 | 12j | Stability | = | 57 | % | ALA1686965 | % | Homo sapiens | |||
| 20. | ALA1684574 | 12j | IC50 | = | 6 | nM | ALA1686964 | 8.22 | nM | Homo sapiens |
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