# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1770244 | 20 | logD | = | 2.6 | ALA1772492 | ||||||
2. | ALA1770244 | 20 | CL | < | 8 | uL/min/mg | ALA1772497 | mL.min-1.g-1 | Homo sapiens | |||
3. | ALA1770244 | 20 | CL | = | 2.1 | uL/min/10^6cells | ALA1772498 | uL.min-1.(10^6cells)-1 | Homo sapiens | |||
4. | ALA1770244 | 20 | Fu | = | 0.206 | % | ALA1772495 | Homo sapiens | ||||
5. | ALA1770244 | 20 | Fu | = | 0.186 | % | ALA1772496 | Rattus norvegicus | ||||
6. | ALA1770244 | 20 | IC50 | = | 1.07 | nM | ALA1772493 | 8.97 | nM | Homo sapiens | ||
7. | ALA1770244 | 20 | IC50 | = | 506 | nM | ALA1772494 | 6.30 | nM | Homo sapiens | ||
8. | ALA1770244 | 20 | CL | = | 37.1 | ml/min.kg | ALA1772501 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA1770244 | 20 | Vdss | = | 1.71 | L/Kg | ALA1771929 | L.kg-1 | Rattus norvegicus | |||
10. | ALA1770244 | 20 | t1/2 | = | 0.96 | hr | ALA1771930 | hr | Rattus norvegicus |