# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1770317 | 6b | pKi | = | 8 | ALA2039059 | 8.00 | nM | Homo sapiens | |||
2. | ALA1770317 | 6b | pKi | = | 8 | ALA2039058 | 8.00 | nM | Rattus norvegicus | |||
3. | ALA1770317 | 6b | pKi | < | 4.3 | ALA2039030 | nM | Homo sapiens | ||||
4. | ALA1770317 | 6b | pKi | = | 7.7 | ALA2039031 | 7.70 | nM | ||||
5. | ALA1770317 | 6b | pKi | = | 8.3 | ALA2039039 | 8.30 | nM | Homo sapiens | |||
6. | ALA1770317 | 6b | t1/2 | = | 4 | hr | ALA2039040 | hr | Rattus norvegicus | |||
7. | ALA1770317 | 6b | CL | = | 2.6 | ml/min.kg | ALA2039041 | mL.min-1.kg-1 | Rattus norvegicus | |||
8. | ALA1770317 | 6b | AUC/dose | = | 5.5 | ug.hr/mL/mg/kg | ALA2039057 | ug.hr/mL/mg/kg | Rattus norvegicus | |||
9. | ALA1770317 | 6b | F | = | 83 | % | ALA2038927 | % | Rattus norvegicus | |||
10. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039056 | nM | Homo sapiens | ||||
11. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039055 | nM | Homo sapiens | ||||
12. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039053 | nM | Homo sapiens | ||||
13. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039054 | nM | Homo sapiens | ||||
14. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039051 | nM | Homo sapiens | ||||
15. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039052 | nM | Homo sapiens | ||||
16. | ALA1770317 | 6b | solubility | = | 193 | uM | ALA2039049 | nM | ||||
17. | ALA1770317 | 6b | pIC50 | < | 4 | ALA2039050 | nM | Rattus norvegicus | ||||
18. | ALA1770317 | 6b | pIC50 | < | 4 | ALA2039048 | nM | Rattus norvegicus | ||||
19. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039047 | nM | Homo sapiens | ||||
20. | ALA1770317 | 6b | pIC50 | < | 4.3 | ALA2039046 | nM | Homo sapiens |