# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1771259 | 2f, CP-671906 | Drug uptake | = | 17 | nM | ALA1772071 | nM | Rattus norvegicus | |||
2. | ALA1771259 | 2f, CP-671906 | Drug uptake | = | 26 | nM | ALA1772070 | nM | ||||
3. | ALA1771259 | 2f, CP-671906 | Activity | = | 12 | % | ALA1772033 | % | Rattus norvegicus | |||
4. | ALA1771259 | 2f, CP-671906 | INH | < | 50 | % | ALA1772032 | % | Homo sapiens | |||
5. | ALA1771259 | 2f, CP-671906 | IC50 | > | 10000 | nM | ALA1772031 | nM | Homo sapiens | |||
6. | ALA1771259 | 2f, CP-671906 | IC50 | > | 10000 | nM | ALA1772030 | nM | Homo sapiens | |||
7. | ALA1771259 | 2f, CP-671906 | Cp | = | 95 | nM | ALA1772029 | nM | Rattus norvegicus | |||
8. | ALA1771259 | 2f, CP-671906 | Activity | 0 | ALA1772028 | Non-toxic | Rattus norvegicus | |||||
9. | ALA1771259 | 2f, CP-671906 | Activity | 0 | ALA1771977 | Active | Rattus norvegicus | |||||
10. | ALA1771259 | 2f, CP-671906 | Activity | 0 | ALA1771976 | Non-toxic | Rattus norvegicus | |||||
11. | ALA1771259 | 2f, CP-671906 | Activity | 0 | ALA1771975 | Not Active | Rattus norvegicus | |||||
12. | ALA1771259 | 2f, CP-671906 | Activity | = | 12 | % | ALA1771974 | % | Rattus norvegicus | |||
13. | ALA1771259 | 2f, CP-671906 | Activity | 0 | ALA1771973 | Active | Rattus norvegicus | |||||
14. | ALA1771259 | 2f, CP-671906 | BPR | = | 9 | ALA1771972 | ||||||
15. | ALA1771259 | 2f, CP-671906 | BPR | = | 0.1 | ALA1771971 | ||||||
16. | ALA1771259 | 2f, CP-671906 | BPR | = | 0.13 | ALA1771970 | ||||||
17. | ALA1771259 | 2f, CP-671906 | F | = | 13 | % | ALA1771969 | % | Rattus norvegicus | |||
18. | ALA1771259 | 2f, CP-671906 | t1/2 | = | 1.2 | hr | ALA1771968 | hr | Rattus norvegicus | |||
19. | ALA1771259 | 2f, CP-671906 | INH | = | 92 | % | ALA1771967 | % | Rattus norvegicus | |||
20. | ALA1771259 | 2f, CP-671906 | Cp | = | 763 | ml/min.kg | ALA1771966 | mL.min-1.kg-1 | Rattus norvegicus |