# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1782369 | 6 | IC50 | = | 230 | nM | ALA3110613 | 6.64 | nM | Homo sapiens | ||
2. | ALA1782369 | 6 | INH | 0 | ALA3110611 | Not Active | % | Rattus norvegicus | ||||
3. | ALA1782369 | 6 | Cmax | = | 2723 | ng/ml | ALA3110574 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
4. | ALA1782369 | 6 | Tmax | = | 1.5 | hr | ALA3110573 | hr | Rattus norvegicus | |||
5. | ALA1782369 | 6 | AUC | = | 10893 | ng.hr/ml | ALA3110572 | ng.hr.mL-1 | Rattus norvegicus | |||
6. | ALA1782369 | 6 | AUC | = | 28169 | ng.hr/ml | ALA3110571 | ng.hr.mL-1 | Rattus norvegicus | |||
7. | ALA1782369 | 6 | t1/2 | = | 3.9 | hr | ALA3110570 | hr | Rattus norvegicus | |||
8. | ALA1782369 | 6 | t1/2 | = | 3.9 | hr | ALA3110569 | hr | Rattus norvegicus | |||
9. | ALA1782369 | 6 | CL | = | 278 | ml/hr/kg | ALA3110568 | mL.min-1.kg-1 | Rattus norvegicus | |||
10. | ALA1782369 | 6 | Vdss | = | 1147 | ml/kg | ALA3110567 | L.kg-1 | Rattus norvegicus | |||
11. | ALA1782369 | 6 | F | = | 78 | % | ALA3110566 | % | Rattus norvegicus | |||
12. | ALA1782369 | 6 | CLH | < | 1 | microM/min/mg | ALA3110565 | microM/min/mg | ||||
13. | ALA1782369 | 6 | CLH | < | 1 | microM/min/mg | ALA3110563 | microM/min/mg | ||||
14. | ALA1782369 | 6 | CLH | < | 1 | microM/min/mg | ALA3110564 | microM/min/mg | ||||
15. | ALA1782369 | 6 | CLH | < | 1 | microM/min/mg | ALA3110562 | microM/min/mg | ||||
16. | ALA1782369 | 6 | Stability | 0 | ALA3110561 | Stable | % | |||||
17. | ALA1782369 | 6 | Stability | 0 | ALA3110560 | Stable | % | |||||
18. | ALA1782369 | 6 | Stability | 0 | ALA3110559 | Stable | % | |||||
19. | ALA1782369 | 6 | Stability | 0 | ALA3110558 | Stable | % | |||||
20. | ALA1782369 | 6 | Activity | = | 50 | % | ALA3110557 | % | Mus musculus |