# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1784577 | 32, DSM190 | IC50 | = | 190 | nM | ALA3705388 | 6.72 | 318875 | nM | Plasmodium falciparum (isolate 3D7) | |
2. | ALA1784577 | 32, DSM190 | CLH | < | 5 | uL/min | ALA4481159 | uL/min | ||||
3. | ALA1784577 | 32, DSM190 | CLH | < | 6 | uL/min | ALA4481160 | uL/min | ||||
4. | ALA1784577 | 32, DSM190 | PPB | = | 96.6 | % | ALA4481158 | % | ||||
5. | ALA1784577 | 32, DSM190 | solubility | = | 9 | uM | ALA4481157 | nM | ||||
6. | ALA1784577 | 32, DSM190 | logD | = | 2.9 | ALA4481156 | ||||||
7. | ALA1784577 | 32, DSM190 | IC50 | > | 30 | uM | ALA4481155 | nM | Homo sapiens | |||
8. | ALA1784577 | 32, DSM190 | IC50 | = | 0.19 | uM | ALA4481154 | 6.72 | nM | |||
9. | ALA1784577 | 32, DSM190 | solubility | = | 9 | uM | ALA1785549 | nM | ||||
10. | ALA1784577 | 32, DSM190 | logD | = | 2.9 | ALA1785548 | ||||||
11. | ALA1784577 | 32, DSM190 | PPB | = | 97.3 | % | ALA1785553 | % | Rattus norvegicus | |||
12. | ALA1784577 | 32, DSM190 | Activity | 0 | ALA1785739 | Non-toxic | Rattus norvegicus | |||||
13. | ALA1784577 | 32, DSM190 | Activity | 0 | ALA1785738 | Non-toxic | Rattus norvegicus | |||||
14. | ALA1784577 | 32, DSM190 | Activity | 0 | ALA1785556 | Non-toxic | Mus musculus | |||||
15. | ALA1784577 | 32, DSM190 | Ratio | = | 10 | ALA1785546 | ||||||
16. | ALA1784577 | 32, DSM190 | EC50 | = | 0.22 | uM | ALA1785545 | 6.66 | nM | Plasmodium falciparum | ||
17. | ALA1784577 | 32, DSM190 | IC50 | = | 0.19 | uM | ALA1785541 | 6.72 | nM | Plasmodium falciparum | ||
18. | ALA1784577 | 32, DSM190 | IC50 | = | 0.28 | uM | ALA1785542 | 6.55 | nM | |||
19. | ALA1784577 | 32, DSM190 | IC50 | > | 30 | uM | ALA1785543 | nM | Homo sapiens | |||
20. | ALA1784577 | 32, DSM190 | EC50 | = | 1.1 | uM | ALA1785544 | 5.96 | nM | Plasmodium falciparum |