# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1784578 | 33, DSM159 | IC50 | = | 32 | nM | ALA3705388 | 7.50 | 318900 | nM | Plasmodium falciparum (isolate 3D7) | |
2. | ALA1784578 | 33, DSM159 | IC50 | = | 100 | nM | ALA3705388 | 7.00 | 318882 | nM | Plasmodium falciparum (isolate 3D7) | |
3. | ALA1784578 | 33, DSM159 | solubility | = | 89 | uM | ALA1785549 | nM | ||||
4. | ALA1784578 | 33, DSM159 | logD | = | 3.4 | ALA1785548 | ||||||
5. | ALA1784578 | 33, DSM159 | Activity | 0 | ALA1785556 | Non-toxic | Mus musculus | |||||
6. | ALA1784578 | 33, DSM159 | Ratio IC50 | = | 5 | ALA1785547 | ||||||
7. | ALA1784578 | 33, DSM159 | IC50 | = | 0.064 | uM | ALA1785541 | 7.19 | nM | Plasmodium falciparum | ||
8. | ALA1784578 | 33, DSM159 | IC50 | = | 0.19 | uM | ALA1785542 | 6.72 | nM | |||
9. | ALA1784578 | 33, DSM159 | IC50 | > | 100 | uM | ALA1785543 | nM | Homo sapiens | |||
10. | ALA1784578 | 33, DSM159 | EC50 | = | 0.16 | uM | ALA1785544 | 6.80 | nM | Plasmodium falciparum | ||
11. | ALA1784578 | 33, DSM159 | Time | = | 1 | hr | ALA1785555 | hr | Mus musculus | |||
12. | ALA1784578 | 33, DSM159 | Cmax | = | 2.2 | uM | ALA1785554 | nM | Mus musculus | |||
13. | ALA1784578 | 33, DSM159 | CL | = | 361 | uL/min/mg | ALA1785552 | mL.min-1.g-1 | Mus musculus | |||
14. | ALA1784578 | 33, DSM159 | CL | = | 72 | uL/min/mg | ALA1785551 | mL.min-1.g-1 | Homo sapiens | |||
15. | ALA1784578 | 33, DSM159 | PPB | = | 95.5 | % | ALA1785550 | % | Homo sapiens |