# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1795567 | 3b | Vd | = | 1 | L/Kg | ALA1799231 | L.kg-1 | Mus musculus | |||
2. | ALA1795567 | 3b | CL | = | 43 | ml/min.kg | ALA1799230 | mL.min-1.kg-1 | Mus musculus | |||
3. | ALA1795567 | 3b | AUC/dose | = | 0.98 | uM/hr/Kg/mg | ALA1799229 | uM/hr/Kg/mg | Mus musculus | |||
4. | ALA1795567 | 3b | t1/2 | = | 0.54 | hr | ALA1799228 | hr | Mus musculus | |||
5. | ALA1795567 | 3b | Activity | 0 | ALA1799227 | Not Active | Acinetobacter baumannii | |||||
6. | ALA1795567 | 3b | Activity | 0 | ALA1799226 | Active | Acinetobacter baumannii | |||||
7. | ALA1795567 | 3b | Activity | 0 | ALA1799225 | Not Active | Pseudomonas aeruginosa | |||||
8. | ALA1795567 | 3b | Activity | 0 | ALA1799224 | Dose-dependent effect | Pseudomonas aeruginosa | |||||
9. | ALA1795567 | 3b | Activity | 0 | ALA1799223 | Active | Pseudomonas aeruginosa | |||||
10. | ALA1795567 | 3b | IC50 | = | 17 | uM | ALA1799222 | 4.77 | nM | Acinetobacter baumannii | ||
11. | ALA1795567 | 3b | IC50 | = | 0.032 | uM | ALA1799221 | 7.50 | nM | Enterobacter cloacae | ||
12. | ALA1795567 | 3b | IC50 | = | 0.008 | uM | ALA1799220 | 8.12 | nM | Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) | ||
13. | ALA1795567 | 3b | IC50 | = | 22 | uM | ALA1799219 | 4.66 | nM | Klebsiella pneumoniae | ||
14. | ALA1795567 | 3b | IC50 | = | 28 | uM | ALA1799218 | 4.55 | nM |