# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | CHR-3996 | 21r, CHR-3996 | Ki | = | 4.8 | nM | ALA1804309 | 8.32 | nM | Homo sapiens | ||
2. | CHR-3996 | 21r, CHR-3996 | Activity | 0 | ALA1805467 | Active | Homo sapiens | |||||
3. | CHR-3996 | 21r, CHR-3996 | Activity | 0 | ALA1805466 | Active | Homo sapiens | |||||
4. | CHR-3996 | 21r, CHR-3996 | Drug uptake | = | 133 | ng/ml | ALA1805464 | ng/ml | ||||
5. | CHR-3996 | 21r, CHR-3996 | Activity | 0 | ALA1805463 | Active | Homo sapiens | |||||
6. | CHR-3996 | 21r, CHR-3996 | Activity | = | 48 | % | ALA1805373 | % | Homo sapiens | |||
7. | CHR-3996 | 21r, CHR-3996 | Activity | = | 21 | % | ALA1805372 | % | Homo sapiens | |||
8. | CHR-3996 | 21r, CHR-3996 | Activity | = | 10 | % | ALA1805371 | % | Homo sapiens | |||
9. | CHR-3996 | 21r, CHR-3996 | Activity | = | 21 | % | ALA1805370 | % | Homo sapiens | |||
10. | CHR-3996 | 21r, CHR-3996 | RatioGI50 | = | 5 | ALA1805369 | ||||||
11. | CHR-3996 | 21r, CHR-3996 | RatioGI50 | = | 5 | ALA1805237 | Homo sapiens | |||||
12. | CHR-3996 | 21r, CHR-3996 | RatioGI50 | = | 5 | ALA1805236 | Homo sapiens | |||||
13. | CHR-3996 | 21r, CHR-3996 | RatioGI50 | = | 5 | ALA1805235 | Homo sapiens | |||||
14. | CHR-3996 | 21r, CHR-3996 | RatioGI50 | = | 5 | ALA1805234 | Homo sapiens | |||||
15. | CHR-3996 | 21r, CHR-3996 | IC50 | = | 8 | nM | ALA1804309 | 8.10 | nM | Homo sapiens | ||
16. | CHR-3996 | 21r, CHR-3996 | GI50 | = | 72 | nM | ALA1804310 | nM | Homo sapiens | |||
17. | CHR-3996 | 21r, CHR-3996 | Ratio | = | 9 | ALA1804533 | ||||||
18. | CHR-3996 | 21r, CHR-3996 | AUCt | = | 93 | ng.hr/ml | ALA1804534 | ng.hr.mL-1 | Mus musculus | |||
19. | CHR-3996 | 21r, CHR-3996 | AUCt | = | 775 | ng.hr/ml | ALA1804535 | ng.hr.mL-1 | Mus musculus | |||
20. | CHR-3996 | 21r, CHR-3996 | Ratio | = | 8.3 | ALA1804536 | Mus musculus |