# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1802185 | 17b | MIC90 | = | 0.61 | ug ml-1 | ALA2067384 | ug.mL-1 | Escherichia coli | |||
2. | ALA1802185 | 17b | IC90 | = | 1.4 | uM | ALA2067384 | nM | Escherichia coli | |||
3. | ALA1802185 | 17b | IC50 | = | 0.33 | uM | ALA2067384 | 6.48 | nM | Escherichia coli | ||
4. | ALA1802185 | 17b | log10cfu | = | 0.7 | ALA2067398 | Escherichia coli | |||||
5. | ALA1802185 | 17b | log10cfu | = | 4 | ALA2067395 | Escherichia coli | |||||
6. | ALA1802185 | 17b | PPB | = | 89 | % | ALA2067383 | % | Homo sapiens | |||
7. | ALA1802185 | 17b | permeability | 0 | ALA2067382 | impermeable | ||||||
8. | ALA1802185 | 17b | IC50 | = | 6.7 | nM | ALA2067399 | 8.17 | nM | |||
9. | ALA1802185 | 17b | Ratio IC50 | = | 0.13 | ALA2067379 | Escherichia coli | |||||
10. | ALA1802185 | 17b | IC50 | = | 10 | uM | ALA2067378 | 5.00 | nM | Escherichia coli | ||
11. | ALA1802185 | 17b | logD | = | -0.8 | ALA2067380 | ||||||
12. | ALA1802185 | 17b | pKa | = | 3.98 | ALA1805239 | ||||||
13. | ALA1802185 | 17b | permeability | 0 | ALA1805241 | impermeable | ||||||
14. | ALA1802185 | 17b | AUC | = | 2.7 | ug.hr/ml | ALA1805327 | ng.hr.mL-1 | ||||
15. | ALA1802185 | 17b | AUC | 0 | ALA1805326 | Not Determined | Mus musculus | |||||
16. | ALA1802185 | 17b | PPB | = | 89 | % | ALA1805325 | % | Mus musculus | |||
17. | ALA1802185 | 17b | AUC | = | 209.6 | ug.hr/ml | ALA1805324 | ng.hr.mL-1 | ||||
18. | ALA1802185 | 17b | AUC | = | 20.8 | ug.hr/ml | ALA1805323 | ng.hr.mL-1 | Mus musculus | |||
19. | ALA1802185 | 17b | Cmax | = | 588.4 | ug ml-1 | ALA1805322 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
20. | ALA1802185 | 17b | Cmax | = | 39.4 | ug ml-1 | ALA1805251 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus |