| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1802186 | 17a | permeability | 0 | ALA1805241 | impermeable | ||||||
| 2. | ALA1802186 | 17a | PPB | = | 73 | % | ALA1805325 | % | Mus musculus | |||
| 3. | ALA1802186 | 17a | AUC | = | 139.9 | ug.hr/ml | ALA1805324 | ng.hr.mL-1 | ||||
| 4. | ALA1802186 | 17a | AUC | = | 19.3 | ug.hr/ml | ALA1805323 | ng.hr.mL-1 | Mus musculus | |||
| 5. | ALA1802186 | 17a | Cmax | = | 509.6 | ug ml-1 | ALA1805322 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 6. | ALA1802186 | 17a | Cmax | = | 34.4 | ug ml-1 | ALA1805251 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 7. | ALA1802186 | 17a | Stability | 0 | ALA1805249 | Stable | % | Mus musculus | ||||
| 8. | ALA1802186 | 17a | Papp | 0 | ALA1805243 | Not Determined | Homo sapiens | |||||
| 9. | ALA1802186 | 17a | Activity | 0 | ALA1805238 | Not Active | Homo sapiens | |||||
| 10. | ALA1802186 | 17a | Activity | 0 | ALA1805068 | Not Active | Homo sapiens | |||||
| 11. | ALA1802186 | 17a | Activity | 0 | ALA1805479 | Active | Escherichia coli | |||||
| 12. | ALA1802186 | 17a | Activity | 0 | ALA1805478 | Active | Escherichia coli | |||||
| 13. | ALA1802186 | 17a | Therm_solubility | > | 3000 | ug ml-1 | ALA1805244 | ug.mL-1 | ||||
| 14. | ALA1802186 | 17a | Ratio IC50 | = | 0.15 | ALA1805066 | Escherichia coli K-12 | |||||
| 15. | ALA1802186 | 17a | PPB | = | 73 | % | ALA1805250 | % | Homo sapiens | |||
| 16. | ALA1802186 | 17a | pKa | = | 3.88 | ALA1805239 | ||||||
| 17. | ALA1802186 | 17a | logD | < | -1.5 | ALA1805240 | ||||||
| 18. | ALA1802186 | 17a | IC50 | = | 17.1 | nM | ALA1805065 | 7.77 | nM | Escherichia coli K-12 | ||
| 19. | ALA1802186 | 17a | IC50 | = | 45 | uM | ALA1805067 | 4.35 | nM | Escherichia coli K-12 | ||
| 20. | ALA1802186 | 17a | FC | = | 4.5 | ALA1805331 | Escherichia coli |
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