# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1807446 | 24 | IC50 | = | 4 | nM | ALA4337359 | 8.40 | nM | Homo sapiens | ||
2. | ALA1807446 | 24 | INH | 0 | ALA1811287 | Active | % | Mus musculus | ||||
3. | ALA1807446 | 24 | AUC | = | 2300 | ng/hr/ml | ALA1811598 | ng.hr.mL-1 | Rattus norvegicus | |||
4. | ALA1807446 | 24 | Cmax | = | 752 | ng/ml | ALA1811596 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
5. | ALA1807446 | 24 | Cp | = | 550 | ng/ml | ALA1811597 | ng/ml | Rattus norvegicus | |||
6. | ALA1807446 | 24 | IC50 | = | 382 | nM | ALA1811286 | 6.42 | nM | Macaca mulatta | ||
7. | ALA1807446 | 24 | IC50 | = | 173 | nM | ALA1811284 | 6.76 | nM | Homo sapiens | ||
8. | ALA1807446 | 24 | INH | = | 95 | % | ALA1811288 | % | Mus musculus | |||
9. | ALA1807446 | 24 | INH | = | 73 | % | ALA1811599 | % | Rattus norvegicus | |||
10. | ALA1807446 | 24 | IC50 | = | 41 | nM | ALA1811283 | 7.39 | nM | Homo sapiens | ||
11. | ALA1807446 | 24 | IC50 | = | 21 | nM | ALA1811285 | 7.68 | nM | Homo sapiens | ||
12. | ALA1807446 | 24 | IC50 | = | 19 | nM | ALA1811289 | 7.72 | nM | Homo sapiens | ||
13. | ALA1807446 | 24 | IC50 | = | 4 | nM | ALA1811277 | 8.40 | nM | Homo sapiens | ||
14. | ALA1807446 | 24 | CL | = | 0.08 | nmol/min/mg | ALA1811281 | nmol/min/mg | Homo sapiens | |||
15. | ALA1807446 | 24 | IC50 | > | 25 | uM | ALA1811591 | nM | Homo sapiens | |||
16. | ALA1807446 | 24 | IC50 | > | 25 | uM | ALA1811590 | nM | Homo sapiens | |||
17. | ALA1807446 | 24 | IC50 | > | 25 | uM | ALA1811589 | nM | Homo sapiens | |||
18. | ALA1807446 | 24 | IC50 | > | 25 | uM | ALA1811588 | nM | Homo sapiens | |||
19. | ALA1807446 | 24 | IC50 | > | 25 | uM | ALA1811587 | nM | Homo sapiens | |||
20. | ALA1807446 | 24 | IC50 | > | 25 | uM | ALA1811586 | nM | Homo sapiens |