Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA1809039	11a	Tmax/dose	=	3.1	hr	ALA1810383		hr	Rattus norvegicus
2.	ALA1809039	11a	Cmax/dose	=	137	nM	ALA1810382		nM	Rattus norvegicus
3.	ALA1809039	11a	F	=	97	%	ALA1810381		%	Rattus norvegicus
4.	ALA1809039	11a	AUC/dose	=	2658	nM.hr	ALA1810333		nM.hr	Rattus norvegicus
5.	ALA1809039	11a	AUC/dose	=	2729	nM.hr	ALA1810332		nM.hr	Rattus norvegicus
6.	ALA1809039	11a	beta t1/2	=	8.9	hr	ALA1810331		hr	Rattus norvegicus
7.	ALA1809039	11a	Vdss(app)	=	8.3	L/Kg	ALA1810330		L.kg-1	Rattus norvegicus
8.	ALA1809039	11a	CL	=	13	ml/min.kg	ALA1810329		mL.min-1.kg-1	Rattus norvegicus
9.	ALA1809039	11a	IC50	>	30	uM	ALA1810316		nM	Homo sapiens
10.	ALA1809039	11a	solubility	>	1	mM	ALA1810328		nM
11.	ALA1809039	11a	IC50	>	2500	nM	ALA1810327		nM
12.	ALA1809039	11a	IC50	>	2500	nM	ALA1810326		nM
13.	ALA1809039	11a	IC50	>	2500	nM	ALA1810325		nM
14.	ALA1809039	11a	Fu	=	7	%	ALA1810324			Homo sapiens
15.	ALA1809039	11a	Fu	=	4	%	ALA1810323			Rattus norvegicus
16.	ALA1809039	11a	IC50	=	5	nM	ALA1810317	8.30	nM	Rattus norvegicus
17.	ALA1809039	11a	IC50	=	2	nM	ALA1810321	8.70	nM	Mus musculus
18.	ALA1809039	11a	IC50	=	2	nM	ALA1810320	8.70	nM	Homo sapiens
19.	ALA1809039	11a	IC50	=	2	nM	ALA1810319	8.70	nM	Homo sapiens