# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | LM 10 | 58 | CC50 | > | 20 | uM | ALA4296191 | Median N= 2; Maxinhib 15.4 Pct | nM | Homo sapiens | ||
2. | LM 10 | 58 | HC10 | > | 20 | uM | ALA4296784 | Median N= 2; Maxinhib 4.8 Pct | uM | |||
3. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296184 | Median N= 2; Maxinhib 11.4 Pct | nM | Staphylococcus aureus | ||
4. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296802 | Median N= 2; Maxinhib 18.4 Pct | nM | Pseudomonas aeruginosa | ||
5. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296188 | Median N= 2; Maxinhib 22.5 Pct | nM | Acinetobacter baumannii | ||
6. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296187 | Median N= 2; Maxinhib 16.9 Pct | nM | Pseudomonas aeruginosa | ||
7. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296186 | Median N= 2; Maxinhib 0.5 Pct | nM | Klebsiella pneumoniae | ||
8. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296185 | Median N= 2; Maxinhib 13.1 Pct | nM | Escherichia coli | ||
9. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296190 | Median N= 2; Maxinhib 1.7 Pct | nM | Cryptococcus neoformans | ||
10. | LM 10 | 58 | MIC | > | 20 | uM | ALA4296189 | Median N= 2; Maxinhib 17.6 Pct | nM | Candida albicans | ||
11. | LM 10 | 58 | Drug metabolism | 0 | ALA4810622 | Metabolite_Detected | ||||||
12. | LM 10 | 58 | Drug metabolism | 0 | ALA4810621 | Metabolite_Detected | ||||||
13. | LM 10 | 58 | INH | 0 | ALA4810620 | Not Active | % | Homo sapiens | ||||
14. | LM 10 | 58 | INH | 0 | ALA4810619 | Not Active | % | Homo sapiens | ||||
15. | LM 10 | 58 | t1/2 | > | 1440 | min | ALA4810618 | hr | ||||
16. | LM 10 | 58 | LD50 | > | 100 | uM | ALA4810617 | uM | Mus musculus | |||
17. | LM 10 | 58 | IC50 | = | 1.74 | uM | ALA4810616 | 5.76 | nM | Homo sapiens | ||
18. | LM 10 | 58 | IC50 | = | 6.1 | uM | ALA4810615 | 5.21 | nM | Homo sapiens | ||
19. | LM 10 | 58 | Ki | = | 5.6 | uM | ALA4383521 | 5.25 | nM | Homo sapiens | ||
20. | LM 10 | 58 | IC50 | = | 0.398 | uM | ALA4383519 | 6.40 | nM | Homo sapiens |