# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1819603 | 2a | Ki | = | 310 | nM | ALA1918134 | 6.51 | nM | Mus musculus | ||
2. | ALA1819603 | 2a | Ki | = | 6400 | nM | ALA1918135 | 5.19 | nM | Homo sapiens | ||
3. | ALA1819603 | 2a | IC50 | = | 220 | nM | ALA1918136 | 6.66 | nM | Mus musculus | ||
4. | ALA1819603 | 2a | F | = | 119 | % | ALA1821240 | % | Rattus norvegicus | |||
5. | ALA1819603 | 2a | Vdss | = | 220 | L/Kg | ALA1821239 | L.kg-1 | Rattus norvegicus | |||
6. | ALA1819603 | 2a | t1/2 | = | 1.8 | hr | ALA1821238 | hr | Rattus norvegicus | |||
7. | ALA1819603 | 2a | t1/2 | = | 0.27 | hr | ALA1821237 | hr | Rattus norvegicus | |||
8. | ALA1819603 | 2a | CL | = | 25 | ml/min.kg | ALA1821235 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA1819603 | 2a | Cmax | = | 4.9 | ug ml-1 | ALA1821236 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
10. | ALA1819603 | 2a | AUC | = | 8 | microg.hr/mL | ALA1821232 | ng.hr.mL-1 | Rattus norvegicus | |||
11. | ALA1819603 | 2a | AUC | = | 0.67 | microg.hr/mL | ALA1821231 | ng.hr.mL-1 | Rattus norvegicus | |||
12. | ALA1819603 | 2a | IC50 | = | 220 | nM | ALA1821228 | 6.66 | nM | Mus musculus | ||
13. | ALA1819603 | 2a | Ki | = | 310 | nM | ALA1821227 | 6.51 | nM | Mus musculus | ||
14. | ALA1819603 | 2a | Ki | = | 6400 | nM | ALA1821226 | 5.19 | nM | Homo sapiens | ||
15. | ALA1819603 | 2a | Ki | > | 10000 | nM | ALA1821225 | nM | Mus musculus | |||
16. | ALA1819603 | 2a | Ki | > | 10000 | nM | ALA1821224 | nM | Mus musculus | |||
17. | ALA1819603 | 2a | Ki | = | 520 | nM | ALA1821223 | 6.28 | nM | Mus musculus | ||
18. | ALA1819603 | 2a | Ki | = | 2100 | nM | ALA1821222 | 5.68 | nM | Mus musculus |