| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1822067 | 1 | TGI | = | 76 | % | ALA2049552 | % | Homo sapiens | |||
| 2. | ALA1822067 | 1 | ED90 | = | 139 | mg kg-1 | ALA2049552 | mg kg-1 | Homo sapiens | |||
| 3. | ALA1822067 | 1 | ED50 | = | 25.2 | mg kg-1 | ALA2049552 | mg.kg-1 | Homo sapiens | |||
| 4. | ALA1822067 | 1 | Therm_solubility | = | 9 | ug ml-1 | ALA2050511 | ug.mL-1 | ||||
| 5. | ALA1822067 | 1 | Therm_solubility | = | 4 | ug ml-1 | ALA2050460 | ug.mL-1 | ||||
| 6. | ALA1822067 | 1 | Therm_solubility | = | 3 | ug ml-1 | ALA2050459 | ug.mL-1 | ||||
| 7. | ALA1822067 | 1 | pKa | = | 0.7 | ALA2050458 | ||||||
| 8. | ALA1822067 | 1 | pKa | = | 0.7 | ALA2050457 | ||||||
| 9. | ALA1822067 | 1 | IC50 | = | 19 | nM | ALA2050456 | 7.72 | nM | Homo sapiens | ||
| 10. | ALA1822067 | 1 | IC50 | = | 5 | nM | ALA2050455 | 8.30 | nM | Homo sapiens | ||
| 11. | ALA1822067 | 1 | AUC | = | 105 | uM.hr | ALA2034094 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 12. | ALA1822067 | 1 | solubility | = | 3 | ug ml-1 | ALA2034093 | ug.mL-1 | ||||
| 13. | ALA1822067 | 1 | Vd | = | 0.11 | L/Kg | ALA2034092 | L.kg-1 | Mus musculus | |||
| 14. | ALA1822067 | 1 | F | = | 48 | % | ALA2034091 | % | Mus musculus | |||
| 15. | ALA1822067 | 1 | CL | = | 1.3 | ml/min.kg | ALA2034090 | mL.min-1.kg-1 | Mus musculus | |||
| 16. | ALA1822067 | 1 | AUC | = | 426 | uM.hr | ALA2034089 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
| 17. | ALA1822067 | 1 | solubility | = | 9 | ug ml-1 | ALA2034088 | ug.mL-1 | ||||
| 18. | ALA1822067 | 1 | solubility | = | 4 | ug ml-1 | ALA2034087 | ug.mL-1 | ||||
| 19. | ALA1822067 | 1 | INH | = | 88 | % | ALA2034083 | % | Homo sapiens | |||
| 20. | ALA1822067 | 1 | INH | = | 83 | % | ALA2034082 | % | Homo sapiens |
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