# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1823895 | KCN1 | IC50 | = | 0.59 | uM | ALA4010988 | 6.23 | nM | |||
2. | ALA1823895 | KCN1 | FC | = | 6 | ALA4010987 | Homo sapiens | |||||
3. | ALA1823895 | KCN1 | IC50 | = | 0.6 | uM | ALA4010986 | 6.22 | nM | |||
4. | ALA1823895 | KCN1 | IC50 | = | 0.59 | uM | ALA4481812 | 6.23 | nM | Homo sapiens | ||
5. | ALA1823895 | KCN1 | Activity | 0 | ALA2173110 | Active | Homo sapiens | |||||
6. | ALA1823895 | KCN1 | Activity | 0 | ALA2173111 | Not Active | Homo sapiens | |||||
7. | ALA1823895 | KCN1 | Kd | = | 345 | nM | ALA2173108 | 6.46 | nM | Homo sapiens | ||
8. | ALA1823895 | KCN1 | solubility | = | 0.009 | uM | ALA2168933 | nM | ||||
9. | ALA1823895 | KCN1 | INH | 0 | ALA2168934 | Active | % | Homo sapiens | ||||
10. | ALA1823895 | KCN1 | INH | 0 | ALA2168936 | Not Active | % | Homo sapiens | ||||
11. | ALA1823895 | KCN1 | solubility | = | 0.009 | uM | ALA2169666 | nM | ||||
12. | ALA1823895 | KCN1 | t1/2 | = | 11 | hr | ALA2169670 | hr | Mus musculus | |||
13. | ALA1823895 | KCN1 | Activity | = | 28 | % | ALA2169671 | % | Homo sapiens | |||
14. | ALA1823895 | KCN1 | logP | = | 3.7 | ALA2169665 | ||||||
15. | ALA1823895 | KCN1 | solubility | < | 15 | ug ml-1 | ALA2169667 | ug.mL-1 | ||||
16. | ALA1823895 | KCN1 | solubility | < | 15 | ug ml-1 | ALA2169668 | ug.mL-1 | ||||
17. | ALA1823895 | KCN1 | solubility | < | 15 | ug ml-1 | ALA2169669 | ug.mL-1 | ||||
18. | ALA1823895 | KCN1 | Drug metabolism | < | 1 | % | ALA2169672 | % | Mus musculus | |||
19. | ALA1823895 | KCN1 | INH | 0 | ALA2060139 | Dose-dependent effect | % | Homo sapiens | ||||
20. | ALA1823895 | KCN1 | solubility | < | 15 | ug ml-1 | ALA2060285 | ug.mL-1 |