| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1824241 | 10t | Ki | = | 0.41 | nM | ALA2378561 | 9.39 | nM | Homo sapiens | ||
| 2. | ALA1824241 | 10t | ED50 | = | 1.3 | mg kg-1 | ALA2378547 | mg.kg-1 | Mus musculus | |||
| 3. | ALA1824241 | 10t | Ki | = | 1.6 | nM | ALA2378560 | 8.80 | nM | Mus musculus | ||
| 4. | ALA1824241 | 10t | t1/2 | = | 2.6 | hr | ALA2378549 | hr | Mus musculus | |||
| 5. | ALA1824241 | 10t | BPR | = | 3.6 | ALA2378542 | ||||||
| 6. | ALA1824241 | 10t | t1/2 | = | 5 | hr | ALA2378554 | hr | Mus musculus | |||
| 7. | ALA1824241 | 10t | t1/2 | > | 10 | hr | ALA2378552 | hr | Mus musculus | |||
| 8. | ALA1824241 | 10t | Tmax | = | 90 | min | ALA2378557 | hr | Mus musculus | |||
| 9. | ALA1824241 | 10t | Tmax | = | 90 | min | ALA2378555 | hr | Mus musculus | |||
| 10. | ALA1824241 | 10t | Cmax | = | 357 | ng/ml | ALA2378556 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 11. | ALA1824241 | 10t | AUC | = | 2107 | ng.hr/ml | ALA2378559 | ng.hr.mL-1 | Mus musculus | |||
| 12. | ALA1824241 | 10t | Cmax | = | 2385 | ng/ml | ALA2378553 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 13. | ALA1824241 | 10t | AUC | = | 15618 | ng.hr/ml | ALA2378558 | ng.hr.mL-1 | Mus musculus | |||
| 14. | ALA1824241 | 10t | Ratio AUC | = | 7.4 | ALA1827196 | ||||||
| 15. | ALA1824241 | 10t | AUC | = | 15618.7 | ng/mL.hr | ALA1827191 | ng.hr.mL-1 | Mus musculus | |||
| 16. | ALA1824241 | 10t | AUC | = | 2107.6 | ng/mL.hr | ALA1827190 | ng.hr.mL-1 | Mus musculus | |||
| 17. | ALA1824241 | 10t | Stability | 0 | ALA1827189 | Stable | % | Mus musculus | ||||
| 18. | ALA1824241 | 10t | Stability | 0 | ALA1827188 | Stable | % | Homo sapiens | ||||
| 19. | ALA1824241 | 10t | ED50 | = | 1.3 | mg kg-1 | ALA1827187 | mg.kg-1 | Mus musculus | |||
| 20. | ALA1824241 | 10t | INH | = | 34 | % | ALA1827186 | % | Homo sapiens |
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