# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1830646 | 26 | Papp | = | 24 | 10'-6 cm/s | ALA1833227 | 10'-6 cm/s | Homo sapiens | |||
2. | ALA1830646 | 26 | AUC | = | 13.9 | ng.hr/ml | ALA1833225 | ng.hr.mL-1 | Mustela putorius furo | |||
3. | ALA1830646 | 26 | Tmax | = | 0.4 | hr | ALA1833223 | hr | Mustela putorius furo | |||
4. | ALA1830646 | 26 | t1/2 | = | 0.5 | hr | ALA1833221 | hr | Mustela putorius furo | |||
5. | ALA1830646 | 26 | Cmax | = | 72 | ng/ml | ALA1833219 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mustela putorius furo | ||
6. | ALA1830646 | 26 | Stability | = | 53 | % | ALA1833218 | % | Homo sapiens | |||
7. | ALA1830646 | 26 | Stability | = | 67 | % | ALA1833217 | % | Rattus norvegicus | |||
8. | ALA1830646 | 26 | Activity | = | 0.1 | mg kg-1 | ALA1833216 | mg kg-1 | Mustela putorius furo | |||
9. | ALA1830646 | 26 | INH | = | 65 | % | ALA1833215 | % | Rattus norvegicus | |||
10. | ALA1830646 | 26 | IC50 | = | 0.5 | nM | ALA1833214 | 9.30 | nM | Homo sapiens | ||
11. | ALA1830646 | 26 | IC50 | = | 12 | nM | ALA1833213 | 7.92 | nM | Homo sapiens | ||
12. | ALA1830646 | 26 | IC50 | = | 0.1 | nM | ALA1833212 | 10.00 | nM | Homo sapiens | ||
13. | ALA1830646 | 26 | IC50 | = | 0.3 | nM | ALA1833211 | 9.52 | nM | Homo sapiens | ||
14. | ALA1830646 | 26 | IC50 | = | 0.1 | nM | ALA1833210 | 10.00 | nM | Homo sapiens |