# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1835153 | 65 | IC50 | = | 300 | nM | ALA1840263 | 6.52 | nM | Homo sapiens | ||
2. | ALA1835153 | 65 | IC50 | = | 0.8 | nM | ALA1840262 | 9.10 | nM | Homo sapiens | ||
3. | ALA1835153 | 65 | IC50 | = | 11 | nM | ALA1840112 | 7.96 | nM | Homo sapiens | ||
4. | ALA1835153 | 65 | IC50 | = | 0.4 | nM | ALA1840111 | 9.40 | nM | Homo sapiens | ||
5. | ALA1835153 | 65 | IC50 | = | 1.2 | uM | ALA1840260 | 5.92 | nM | Mus musculus | ||
6. | ALA1835153 | 65 | Ratio IC50 | = | 25 | ALA1840259 | ||||||
7. | ALA1835153 | 65 | Ratio IC50 | = | 18 | ALA1840258 | ||||||
8. | ALA1835153 | 65 | Ratio IC50 | = | 17 | ALA1840183 | ||||||
9. | ALA1835153 | 65 | Ratio IC50 | = | 13 | ALA1840182 | ||||||
10. | ALA1835153 | 65 | Ratio IC50 | = | 11 | ALA1840181 | ||||||
11. | ALA1835153 | 65 | Activity | 0 | ALA1840261 | Dose-dependent effect | Mus musculus | |||||
12. | ALA1835153 | 65 | Activity | 0 | ALA1840264 | Dose-dependent effect | Mus musculus | |||||
13. | ALA1835153 | 65 | IC50 | = | 1.5 | nM | ALA1840113 | 8.82 | nM | Homo sapiens | ||
14. | ALA1835153 | 65 | Ratio IC50 | > | 50 | ALA1840117 | ||||||
15. | ALA1835153 | 65 | IC50 | = | 22000 | nM | ALA1840125 | 4.66 | nM | Homo sapiens | ||
16. | ALA1835153 | 65 | INH | = | 30 | % | ALA1840126 | % | Homo sapiens | |||
17. | ALA1835153 | 65 | t1/2 | = | 4.5 | hr | ALA1840127 | hr | Rattus norvegicus | |||
18. | ALA1835153 | 65 | IC50 | = | 25 | nM | ALA1840130 | 7.60 | nM | Homo sapiens | ||
19. | ALA1835153 | 65 | CL | = | 7 | ml/min.kg | ALA1840131 | mL.min-1.kg-1 | Rattus norvegicus | |||
20. | ALA1835153 | 65 | INH | = | 34 | % | ALA1840132 | % | Homo sapiens |