# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1835918 | 19 | PPB | 95.12 | % | ALA3301366 | % | |||||
2. | ALA1835918 | 19 | PPB | 93.8 | % | ALA3301365 | % | |||||
3. | ALA1835918 | 19 | CLint | 26.41 | microL/min/1E6 cells | ALA3301372 | uL.min-1.(10^6cells)-1 | |||||
4. | ALA1835918 | 19 | CLint | 26.33 | microL/min/mg | ALA3301370 | mL.min-1.g-1 | |||||
5. | ALA1835918 | 19 | LogD7.4 | 2.62 | ALA3301363 | |||||||
6. | ALA1835918 | 19 | CLint | 6 | microL/min/1E6 cells | ALA3301371 | uL.min-1.(10^6cells)-1 | |||||
7. | ALA1835918 | 19 | Solubility | 128.8 | uM | ALA3301364 | nM | |||||
8. | ALA1835918 | 19 | logD | = | 2.6 | ALA1837160 | ||||||
9. | ALA1835918 | 19 | F | = | 60 | % | ALA1837159 | % | Rattus norvegicus | |||
10. | ALA1835918 | 19 | Vdss | = | 1.5 | L/Kg | ALA1837158 | L.kg-1 | Rattus norvegicus | |||
11. | ALA1835918 | 19 | t1/2 | = | 2.2 | hr | ALA1837157 | hr | Rattus norvegicus | |||
12. | ALA1835918 | 19 | CL | = | 9 | ml/min.kg | ALA1837156 | mL.min-1.kg-1 | Rattus norvegicus | |||
13. | ALA1835918 | 19 | Emax | = | 19 | % | ALA1837155 | % | Homo sapiens | |||
14. | ALA1835918 | 19 | pEC50 | = | 4.5 | ALA1839704 | 4.50 | nM | Homo sapiens | |||
15. | ALA1835918 | 19 | pIC50 | < | 4.3 | ALA1839703 | nM | Homo sapiens | ||||
16. | ALA1835918 | 19 | pIC50 | < | 4.3 | ALA1839702 | nM | Homo sapiens | ||||
17. | ALA1835918 | 19 | pIC50 | < | 4.3 | ALA1839701 | nM | Homo sapiens | ||||
18. | ALA1835918 | 19 | pIC50 | < | 4.3 | ALA1839700 | nM | Homo sapiens | ||||
19. | ALA1835918 | 19 | pIC50 | < | 4.3 | ALA1839699 | nM | Homo sapiens | ||||
20. | ALA1835918 | 19 | pIC50 | < | 5 | ALA1839698 | nM | Homo sapiens |