# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA421 | 18 | IC50 | = | 460 | uM | ALA5250658 | nM | Homo sapiens | |||
2. | ALA421 | 18 | IC50 | = | 450 | uM | ALA5250657 | nM | Homo sapiens | |||
3. | ALA421 | 18 | IC50 | = | 9.6 | uM | ALA5152411 | 5.02 | nM | Homo sapiens | ||
4. | ALA421 | 18 | IC50 | > | 1 | uM | ALA5152410 | nM | Homo sapiens | |||
5. | ALA421 | 18 | IC50 | = | 0.46 | uM | ALA5128691 | 6.34 | nM | Homo sapiens | ||
6. | ALA421 | 18 | Activity | 0 | ALA4477319 | Active | Mus musculus | |||||
7. | ALA421 | 18 | Activity | 0 | ALA4477320 | Active | Mus musculus | |||||
8. | ALA421 | 18 | Activity | 0 | ALA4477307 | Active | Mus musculus | |||||
9. | ALA421 | 18 | Activity | 0 | ALA4477310 | Active | Mus musculus | |||||
10. | ALA421 | 18 | Activity | 0 | ALA4417981 | Active | Rattus norvegicus | |||||
11. | ALA421 | 18 | IC50 | = | 9.6 | uM | ALA4399824 | 5.02 | nM | Homo sapiens | ||
12. | ALA421 | 18 | Kd | = | 7.6 | uM | ALA4393313 | 5.12 | nM | Middle East respiratory syndrome-related coronavirus (isolate UnitedKingdom/H123990006/2012) (Betacoronavirus England 1) (Humancoronavirus EMC) | ||
13. | ALA421 | 18 | Fa | = | 57.99 | % | ALA4374830 | % | ||||
14. | ALA421 | 18 | Peff | = | 0.71 | 10'-6 cm/s | ALA4374829 | 10'-6 cm/s | ||||
15. | ALA421 | 18 | Peff | = | 0.1 | 10'-6 cm/s | ALA4374828 | 10'-6 cm/s | ||||
16. | ALA421 | 18 | inhibition | = | 0.23 | % | ALA4808150 | % | Homo sapiens | |||
17. | ALA421 | 18 | inhibition | = | -21.39 | % | ALA4808149 | % | Homo sapiens | |||
18. | ALA421 | 18 | permeability | = | 0.3 | 10^-6 cm/s | ALA4709032 | 10^-6 cm/s | ||||
19. | ALA421 | 18 | permeability | = | 0.45 | 10^-6 cm/s | ALA4709013 | 10^-6 cm/s | ||||
20. | ALA421 | 18 | Drugabsorption | = | 15.5 | % | ALA4709012 | % |