# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1909725 | 16a | Ki | = | 5.4 | nM | ALA1912470 | 8.27 | nM | Rattus norvegicus | ||
2. | ALA1909725 | 16a | Fu | = | 3.7 | % | ALA1912469 | Rattus norvegicus | ||||
3. | ALA1909725 | 16a | Fu | = | 1.2 | nM | ALA1912468 | nM | Rattus norvegicus | |||
4. | ALA1909725 | 16a | Cp | = | 12 | ng/ml | ALA1912467 | ng/ml | Rattus norvegicus | |||
5. | ALA1909725 | 16a | Drug uptake | = | 4 | ng/g | ALA1912466 | ng/g | Rattus norvegicus | |||
6. | ALA1909725 | 16a | INH | = | 37 | % | ALA1912465 | % | Rattus norvegicus | |||
7. | ALA1909725 | 16a | Cp | = | 24 | ng/ml | ALA1912464 | ng/ml | Rattus norvegicus | |||
8. | ALA1909725 | 16a | Drug uptake | = | 12 | ng/g | ALA1912463 | ng/g | Rattus norvegicus | |||
9. | ALA1909725 | 16a | IC50 | = | 950 | nM | ALA1912462 | 6.02 | nM | Homo sapiens | ||
10. | ALA1909725 | 16a | IC50 | > | 7 | uM | ALA1912461 | nM | Homo sapiens | |||
11. | ALA1909725 | 16a | IC50 | > | 7 | uM | ALA1912460 | nM | Homo sapiens | |||
12. | ALA1909725 | 16a | IC50 | > | 7 | uM | ALA1912459 | nM | Homo sapiens | |||
13. | ALA1909725 | 16a | IC50 | > | 7 | uM | ALA1912458 | nM | Homo sapiens | |||
14. | ALA1909725 | 16a | F | = | 26 | % | ALA1912457 | % | Rattus norvegicus | |||
15. | ALA1909725 | 16a | Vdss | = | 47 | L/Kg | ALA1912456 | L.kg-1 | Rattus norvegicus | |||
16. | ALA1909725 | 16a | CL | = | 8.4 | L/hr/kg | ALA1912455 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA1909725 | 16a | LBF | = | 20 | ml/min | ALA1912454 | ml/min | Rattus norvegicus | |||
18. | ALA1909725 | 16a | LBF | = | 1.5 | L/min | ALA1912453 | L/min | Homo sapiens | |||
19. | ALA1909725 | 16a | CL | = | 110 | ml/min | ALA1912452 | ml/min | Rattus norvegicus | |||
20. | ALA1909725 | 16a | CL | = | 1.8 | L/min | ALA1912451 | L/min | Homo sapiens |