# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1911368 | 28 | Stability | 0 | ALA1912273 | Stable | % | |||||
2. | ALA1911368 | 28 | Stability | 0 | ALA1912272 | Stable | % | |||||
3. | ALA1911368 | 28 | Activity | = | 30 | % | ALA1912270 | % | ||||
4. | ALA1911368 | 28 | F | = | 91 | % | ALA1912267 | % | Rattus norvegicus | |||
5. | ALA1911368 | 28 | Cmax | = | 112.5 | uM | ALA1912266 | nM | Rattus norvegicus | |||
6. | ALA1911368 | 28 | AUC | = | 238.8 | microg.hr/mL | ALA1912265 | ng.hr.mL-1 | Rattus norvegicus | |||
7. | ALA1911368 | 28 | Tmax | = | 1 | hr | ALA1912264 | hr | Rattus norvegicus | |||
8. | ALA1911368 | 28 | CL | = | 3.2 | ml/min.kg | ALA1912263 | mL.min-1.kg-1 | Rattus norvegicus | |||
9. | ALA1911368 | 28 | Vd | = | 0.4 | L/Kg | ALA1912262 | L.kg-1 | Rattus norvegicus | |||
10. | ALA1911368 | 28 | AUC | = | 52.3 | microg.hr/mL | ALA1912261 | ng.hr.mL-1 | Rattus norvegicus | |||
11. | ALA1911368 | 28 | Activity | > | 35 | % | ALA1912269 | % | Mus musculus | |||
12. | ALA1911368 | 28 | Activity | 0 | ALA1912268 | Active | Mus musculus | |||||
13. | ALA1911368 | 28 | Papp | = | 357 | 10'-7 cm/s | ALA1912259 | 10'-7 cm/s | Homo sapiens | |||
14. | ALA1911368 | 28 | logD | = | 2.89 | ALA1912258 | ||||||
15. | ALA1911368 | 28 | solubility | = | 3 | ug ml-1 | ALA1912257 | ug.mL-1 | ||||
16. | ALA1911368 | 28 | INH | 0 | ALA1912255 | Active | % | Homo sapiens | ||||
17. | ALA1911368 | 28 | Ki | = | 0.3 | uM | ALA1912254 | 6.52 | nM | Homo sapiens | ||
18. | ALA1911368 | 28 | Ki | = | 0.3 | uM | ALA1912253 | 6.52 | nM | Homo sapiens | ||
19. | ALA1911368 | 28 | IC50 | = | 1 | uM | ALA1912252 | 6.00 | nM | |||
20. | ALA1911368 | 28 | t1/2 | = | 1.68 | hr | ALA1912260 | hr | Rattus norvegicus |