Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA79433	55	IC50	=	0.42	uM	ALA2352573	6.38	nM	Homo sapiens
2.	ALA79433	55	IC50	=	1	uM	ALA2352572	6.00	nM	Homo sapiens
3.	ALA79433	55	INH	=	91	%	ALA2352571		%	Bos taurus
4.	ALA79433	55	INH	=	91	%	ALA2352569		%	Bos taurus
5.	ALA79433	55	t1/2	=	4.4	hr	ALA1045895		hr	Rattus norvegicus
6.	ALA79433	55	log(10^6/IC50)	=	6		ALA926271			Homo sapiens
7.	ALA79433	55	log(10^6/IC50)	=	6		ALA926270			Homo sapiens
8.	ALA79433	55	log(10^6/IC50)	=	3.1		ALA926269			Homo sapiens
9.	ALA79433	55	Average gross pathology scores+/- SE	=	9.7		ALA631187			Oryctolagus cuniculus
10.	ALA79433	55	Average gross pathology scores+/- SE	=	6.8		ALA631188			Oryctolagus cuniculus
11.	ALA79433	55	CLT	=	0.1	ml min-1 kg-1	ALA625521		mL.min-1.kg-1
12.	ALA79433	55	Vdss	=	0.2	l kg-1	ALA629867		L.kg-1
13.	ALA79433	55	AUC 0	=	1510	ug hr ml-1	ALA628396		ng.hr.mL-1
14.	ALA79433	55	T1/2	=	20.7	hr	ALA635831		hr
15.	ALA79433	55	C0	=	162	ug ml-1	ALA625782		ug ml-1
16.	ALA79433	55	CLT	=	0.1	ml min-1 kg-1	ALA874651		mL.min-1.kg-1	Canis lupus familiaris
17.	ALA79433	55	Vdss	=	0.1	l kg-1	ALA629866		L.kg-1	Canis lupus familiaris
18.	ALA79433	55	AUC 0	=	786	ug hr ml-1	ALA628395		ng.hr.mL-1	Canis lupus familiaris
19.	ALA79433	55	T1/2	=	13.5	hr	ALA635830		hr	Canis lupus familiaris
20.	ALA79433	55	C0	=	82	ug ml-1	ALA628583		ug ml-1	Canis lupus familiaris