Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA1915856	5e	CL	=	1.6	ml/min.kg	ALA1918184			mL.min-1.kg-1	Rattus norvegicus
2.	ALA1915856	5e	F	=	72	%	ALA1918291			%	Rattus norvegicus
3.	ALA1915856	5e	Vdss	=	622	ml/kg	ALA1918290			L.kg-1	Rattus norvegicus
4.	ALA1915856	5e	t1/2	=	5.8	hr	ALA1918289			hr	Rattus norvegicus
5.	ALA1915856	5e	t1/2	=	6.2	hr	ALA1918288			hr	Rattus norvegicus
6.	ALA1915856	5e	Cmax	=	0.93	ug ml-1	ALA1918182		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
7.	ALA1915856	5e	INH	=	46	%	ALA1918140			%	Cavia porcellus
8.	ALA1915856	5e	INH	=	55	%	ALA1918139			%	Cavia porcellus
9.	ALA1915856	5e	Kinetic_solubility	=	407	ug ml-1	ALA1918138			ug.mL-1
10.	ALA1915856	5e	IC50	=	4.4	nM	ALA1918137	8.36		nM	Homo sapiens
11.	ALA1915856	5e	IC50	=	7.6	nM	ALA1918136	8.12		nM	Mus musculus
12.	ALA1915856	5e	Ki	=	6.4	nM	ALA1918134	8.19		nM	Mus musculus
13.	ALA1915856	5e	Ki	>	10000	nM	ALA1918135			nM	Homo sapiens
14.	ALA1915856	5e	AUC	=	8.12	microg.hr/mL	ALA1918180			ng.hr.mL-1	Rattus norvegicus
15.	ALA1915856	5e	AUC	=	11.3	microg.hr/mL	ALA1918181			ng.hr.mL-1	Rattus norvegicus